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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 393 - 393 (1page)
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Biosynthesis of nicotinamide mononucleotide (NMN) is attained by direct conversion of nicotinamide (NAM) with the help of nicotinamide phosphoribosyltransferase (NAMPT) gene via salvage pathway. NMN is intermediate product generated during NAD⁺ biosynthesis. It has long-term pharmacological activities and hence recently it has gained much attention in preclinical studies. The current study has focused on the metabolic engineering of NAMPT, phosphoribosyl pyrophosphate synthetase 1 (PRPS1) and PRPS2 (from Homo sapiens) genes in E. coli. to inve ... 전체 초록 보기
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