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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 108 - 108 (1page)
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초록· 키워드
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Most drug targets belong to five categories, which are G protein-coupled receptors (GPCRs), ion channels, kinases, nuclear hormone receptors and proteases. Among them, approximately 34% of all FDA-approved drugs are targeting GPCR. The GPCR-targeted drug accounts for approximately 27% of the global market share of therapeutic drugs. The hundreds of GPCR-modulating drugs almost all are small molecules. On the other hand, there have not been GPCR-targeted antibodies until Amgen’s erenumab was approved by FDA for the first time in 2018. Because there are lots of challenges to generate su ... 전체 초록 보기
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