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- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 34 - 34 (1page)
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Mono-, di-, and triacetin are three estres of glycerol that are usually synthesized via costly and environmental unfriendly chemical synthesis methods. We metabolically engineered Escherichia coli for the production of mono-, di-, and triacetin using glycerol as a substrate. A novel biosynthetic route of mono- and diacetin is created by overexpression of the native enzyme, maltose O-acetyltransferase (MAA). Then, the biosynthetic pathway is extended to produce a mixture of mono-, di-, and triacetin by overexpression of chloramphenicol-Oacetyltransferase (CAT). By combined strategies of heterologous gene expression, metabolic engineering, and culture optimization, a recombinant E. coli is enabled to produce more ... 전체 초록 보기
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