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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 577 - 577 (1page)
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Extracellular deposits of amyloid-beta(Aβ), a pathological hallmark of Alzheimer’s disease, has been recognized as a potent activator of inflammatory response. To discover neuroprotective compound for AD sourced from natural products, the present study focused on cardamonin from Boesenbergia rotunda. Aβ<SUB>25–35</SUB>-evoked neurotoxicity in PC12 cells as revealed by producing oxidative stress, causing G0/G1 phase arrest during cell cycle progression was attenuated by cardamonin. The compound effectively protected the cells against Aβ-caused apoptosis by alleviating mitochondrial ... 전체 초록 보기
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