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논문 기본 정보

자료유형
학술저널
저자정보
Ito Masanori (Department of General Internal Medicine Hiroshima University Hospital Hiroshima Japan) Tanaka Shinji (Department of Endoscopy Hiroshima University Hospital Hiroshima Japan) Chayama Kazuaki (Department of Gastroenterology and Metabolism Hiroshima University Hospital Hiroshima Japan)
저널정보
거트앤리버 발행위원회 Gut and Liver Gut and Liver 제15권 제3호
발행연도
2021.1
수록면
338 - 345 (8page)

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The prevalence of gastric cancer after eradication (GCAE) is increasing dramatically in Japan. GCAE has characteristic features, and we must understand these features in endoscopic examinations. Differentiated cancer types were frequently found after eradication and included characteristic endoscopic features such as reddish depression (RD). However, benign RD can be difficult to distinguish from gastric cancer because of histological alterations in the surface structures (nonneoplastic epithelium or epithelium with low-grade atypia [ELA]) as well as multiple appearances of RD. Recently, we clarified similar alterations in genetic mutations between ELA and gastric cancer, suggesting that ELA is derived from gastric cancer. Clinically, submucosal invasive cancer was frequently found in patients after eradication therapy even if they received annual endoscopic surveillance. We can improve the diagnostic ability using image-enhanced endoscopy with magnified observation.

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