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논문 기본 정보

자료유형
학술저널
저자정보
Lin Tao (Chinese Academy of Agricultural Sciences) Xiaoyun He (Chinese Academy of Agricultural Sciences) Fengyan Wang (Chinese Academy of Agricultural Sciences) Yingjie Zhong (Chinese Academy of Agricultural Sciences) Linxiang Pan (Ji’nan Laiwu Yingtai Agriculture and Animal Husbandry Technology) Xiangyu Wang (Chinese Academy of Agricultural Sciences) Shangquan Gan (Xinjiang Academy of Agricultural and Reclamation Sciences) Ran Di (Chinese Academy of Agricultural Sciences) Ming-xing Chu (Institute of Animal Sciences Chinese Academy of Agricultural Sciences China)
저널정보
한국축산학회(구 한국동물자원과학회) 한국축산학회지 한국축산학회지 제62권 제6호
발행연도
2020.1
수록면
777 - 789 (13page)

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초록· 키워드

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Intense artificial selection has been imposed to Luzhong mutton sheep population in the past years. Improvements on growth and reproductive performance are two breeding goals in the present herd. Although some progresses were phenotypically observed possibly due to inbreeding induced by strong selection in terms of these traits, the genomic evaluation was poorly understood. Therefore, a high-density SNP array was used to characterize the pattern of runs of homozygosity (ROH), estimate inbreeding and inbreeding depressions on early growth performance and litter size based upon ROH, and scan positive selection signatures of recent population. Consequently, a low inbreeding level was observed which had negative effects on litter size, but not on early growth performance. And 160 genes were under selection, of which some were reported to be linked to several traits of sheep including body weight, litter size, carcass and meat quality, milk yield and composition, fiber quality and health, and the top genes were associated with growth (growth hormone [GH]- growth hormone receptor [GHR]- Insulin-like growth factor 1 [IGF1] axis) and litter size (bone morphogenic proteins [BMPs]-associated). The effectiveness of previous breeding measures was highlighted, but purging selection was proposed to alleviate the inbreeding depression on litter size, providing some genomic insights to breeding management of Luzhong mutton sheep.

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