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논문 기본 정보

자료유형
학술저널
저자정보
Seung Min Kim (국립수산물품질관리원) 이다원 (국립수산물품질관리원) You Jeong Kim (Woogen B&G) Lyu Jin Jun (제주대학교) 박현경 (제주대학교) 김예지 (제주대학교) You Yong Jeong (Woogen B&G) Sung Ho Lee (Woogen B&G) Mun Gyeong Kwon (국립수산물품질관리원) 정준범 (제주대학교)
저널정보
한국수산과학회 Fisheries and Aquatic Sciences Fisheries and Aquatic Sciences 제24권 제4호
발행연도
2021.1
수록면
153 - 162 (10page)

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In this study, a fish metabolic accelerator (a combination of butaphosphan and cyanocobalamin [BPC]) was injected into the muscle of the olive flounder, Paralichthys olivaceus, to investigate its effect on immunity and stress in fish maintained at low temperatures. A single dose of BPC was injected (100 mg/kg body weight) into the olive flounder, and its immunity and stress were observed after one and two weeks. Immunity tests revealed the presence of lysozyme (LZM), nitroblue tetrazolium (NBT), myeloperoxidase (MPO), anti-protease (AP), glutathione peroxidase (GPx), and total immunoglobulin (TIg). BPC injection was found to increase immunity activity compared to the control group. In particular, there was significantly high GPx activity. There was similarly high activity for MPO and GPx in the first week following the injection, followed by significant differences between the BPC-injected and control groups in the second week. There was a reduced low water-temperature stress response in the BPC-injected fish, as evidenced by the cortisol and glucose levels of the control and BPC groups. Lower levels were also observed in the BPC group than the control group during the second week. Cortisol levels were significantly lower in the BPC group than the control group. Histological examinations were conducted in the first and second weeks after the intramuscular injection of the recommended BPC dose to confirm the safety of BPC in aquaculture. There were no abnormalities observed in any tissue samples. This study confirms that the injection of BPC is safe even when used in a culture situation. BPC helps relieve stress and improves non-specific immune responses (innate immunity) in the olive flounder.

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