메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류
인문학
인문학 일반 역사학 철학 종교학 어문학 기타 인문학
사회과학
사회과학 일반 경영학 관광학 교육학 군사학 문헌정보학 법학 사회학 신문방송학 심리과학 정치외교학 지리학 행정학 경제학 무역학 인류학 기타 사회과학
자연과학
자연과학 일반 물리학 생물학 생활과학 수학·통계학 천문학 지구과학 화학 기타 자연과학
공학
공학 일반 건축공학 기계공학 산업공학 재료·에너지공학 전기전자공학 조선해양공학 화학공학 컴퓨터학 기타공학
의약학
의학 일반 간호학 수의학 약학 한의학 기초의학 임상의학 기타 의약학
농수해양학
농수해양학 일반 농학 수산학 식품과학 임학 축산학 해상운송학 기타 농수해양학
예술체육학
예술 일반 디자인 미술 미용 사진 음악학 의상 체육 공연매체예술 기타 예술체육학
복합학
학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

ENG

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Lejia Sun (PUMC and Chinese Academy of Medical Sciences) Wenmo Hu (PUMC and Chinese Academy of Medical Sciences) Meixi Liu (PUMC and Chinese Academy of Medical Sciences) Yang Chen (PUMC and Chinese Academy of Medical Sciences) Bao Jin (PUMC and Chinese Academy of Medical Sciences) Haifeng Xu (PUMC and Chinese Academy of Medical Sciences) Shunda Du (PUMC and Chinese Academy of Medical Sciences) Yiyao Xu (PUMC and Chinese Academy of Medical Sciences) Haitao Zhao (PUMC and Chinese Academy of Medical Sciences) Xin Lu (PUMC and Chinese Academy of Medical Sciences) Xinting Sang (PUMC and Chinese Academy of Medical Sciences) Shouxian Zhong (PUMC and Chinese Academy of Medical Sciences) Huayu Yang (PUMC and Chinese Academy of Medical Sciences) Yilei Mao (PUMC and Chinese Academy of Medical Sciences)
저널정보
대한암학회 Cancer Research and Treatment Cancer Research and Treatment 제52권 제4호
발행연도
2020.1
수록면
1,199 - 1,210 (12page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Purpose The systemic inflammation response index (SIRI) has been reported to have prognostic ability in various solid tumors but has not been studied in gallbladder cancer (GBC). We aimed to determine its prognostic value in GBC. Materials and Methods From 2003 to 2017, patients with confirmed GBC were recruited. To determine the SIRI’s optimal cutoff value, a time-dependent receiver operating characteristic curve was applied. Univariate and multivariate Cox analyses were performed for the recognition of significant factors. Then the cohort was randomly divided into the training and the validation set. A nomogram was constructed using the SIRI and other selected indicators in the training set, and compared with the TNM staging system. C-index, calibration plots, and decision curve analysis were performed to assess the nomogram’s clinical utility. Results One hundred twenty-four patients were included. The SIRI’s optimal cutoff value divided patients into high (≥ 0.89) and low SIRI (< 0.89) groups. Kaplan-Meier curves according to SIRI levels were significantly different (p < 0.001). The high SIRI group tended to stay longer in hospital and lost more blood during surgery. SIRI, body mass index, weight loss, carbohydrate antigen 19-9, radical surgery, and TNM stage were combined to generate a nomogram (C-index, 0.821 in the training cohort, 0.828 in the validation cohort) that was significantly superior to the TNM staging system both in the training (C-index, 0.655) and validation cohort (C-index, 0.649). Conclusion The SIRI is an independent predictor of prognosis in GBC. A nomogram based on the SIRI may help physicians to precisely stratify patients and implement individualized treatment.
#Gallbladder neoplasms #Systemic inflammation response index (SIRI) #Overall survival #Prognosis #Nomogram

목차

등록된 정보가 없습니다.

참고문헌 (30)

참고문헌 신청
de Aretxabala X / 2019 / Biliary spillage a new prognostic factor in gallbladder cancer? / Hepatobiliary Surg Nutr 8:537~538 google schola Buettner S / 2016 / Changing odds of survival over time among patients undergoing surgical resection of gallbladder carcinoma / Ann Surg Oncol 23:4401~4409 google schola 위영준 / 2018 / Trends in Gallbladder Cancer Incidence and Survival in Korea / Cancer Research and Treatment 50(4):1444~1451 dbpia Fortner JG / 1958 / Clinical aspects of primary carcinoma of the gallbladder / AMA Arch Surg 77:742~750 google schola 성유나 / 2020 / Validation of the 8th Edition of the American Joint Committee on Cancer Staging System for Gallbladder Cancer and Implications for the Follow-up of Patients without Node Dissection / Cancer Research and Treatment 52(2):455~468 dbpia

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0