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학술저널
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Emmanuel Kofi Amponsah (Emmanuel Kofi Amponsah and Buyanbileg Sodnom-Ish c) Buyanbileg Sodnom-Ish (Emmanuel Kofi Amponsah and Buyanbileg Sodnom-Ish c) Aaron Sowah Anyetei-Anum (Oral and Maxillofacial Microvascular Reconstructio) Paul Frimpong (Oral and Maxillofacial Microvascular Reconstructio) Soung Min Kim (1.Department of Dentistry School of Dentistry Dental Research Institute Seoul National University S)
저널정보
대한악안면성형재건외과학회 Maxillofacial Plastic Reconstructive Surgery Maxillofacial Plastic Reconstructive Surgery 제43권
발행연도
2021.1
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1 - 4 (4page)

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BackgroundArtemether/lumefantrine (AL), sold under the brand name Coartem, is the most common artemisinin-based combination therapy for the treatment of malaria. Drug-induced oculogyric crisis is a neurological disorder characterized by frequent upward deviations of the eye. In the literature, no cases of Coartem-induced oculogyric crisis have been reported in Ghana. Case presentationA 19-year-old male patient, who presented fever measuring 37.9?°C, general body pains, and weakness was prescribed with antimalarial therapy artemether/lumefantrine, Coartem®, from a local pharmacy. Just after initiation of treatment, the patient complained of double vision, involuntary upward eye deviation, and inability to close both eyes. The patient was diagnosed with Coartem-induced oculogyric crisis and was treated with the cessation of the causing agent and intramuscular injection of promethazine hydrochloride. ConclusionsWhen a patient exhibits a neurological disorder, such as oculogyric crisis, with normal conscious state and normal vital signs, special attention should be given to obtaining a history of recently administered medications. Clinicians should recognize adverse reactions to drugs based on a thorough patient history and examination. The goal of this report was to present Coartem-induced oculogyric crisis.

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