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자료유형
학술저널
저자정보
Harsh Goel (Institute Rotary Cancer Hospital) Ishan Gupta (All India Institute of Medical Sciences) Meenakshi Mourya (Vardhaman Mahavir Medical College & Safdarjung Hospital) Sukhdeep Gill (UPMC Hillman Cancer Center) Anita Chopra (Institute Rotary Cancer Hospital) Amar Ranjan (Institute Rotary Cancer Hospital) Goura Kishor Rath (All India Institute of Medical Sciences) Pranay Tanwar (Institute Rotary Cancer Hospital)
저널정보
대한산부인과학회 Obstetrics & Gynecology Science Obstetrics & Gynecology Science 제64권 제2호
발행연도
2021.1
수록면
174 - 189 (16page)

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The coronavirus disease 2019 (COVID-19) has spread worldwide. It is still a pandemic and poses major health problemacross the globe. In our review, clinical characteristics and laboratory parameters of COVID-19 patients were compiledsystematically, with special reference to pregnant women in order to understand the disease course. An extensiveliterature search on various scientific databases for relevant manuscripts was conducted, which yielded 7 manuscriptsfor final analysis. The most common symptoms were fever (85%), cough (70.63%), chest tightness (37.36%),expectoration (33.27%), fatigue (32%), dyspnea (31.95%), and shortness of breath (31.19%), while hemoptysis (1.0%)was the least common. The associated comorbidities were hypertension (21.6%) and diabetes (10.0%). In terms ofhematological parameters, lower total leukocyte counts were observed in 65% of cases and biochemical parameters,patients demonstrated elevated levels of albumin (53.72%), lactate dehydrogenase (45.71%), and natriuretic peptide(34.84%); however, total bilirubin was elevated in only 8% of cases. In the acute inflammatory cytokine profile,C-reactive protein (59.0%), tumor necrosis factor (58.0%), erythrocyte sedimentation rate (57.0%), interleukin-2 (IL-2, 54.0%), and IL-6 (52.0%) levels were increased, while prolactin levels (6.5%) were minimally elevated. The recoveryrate was approximately 41%, and mortality was about 6.5%. The study also concluded that the clinical symptoms ofCOVID-19 were similar among pregnant and non-pregnant women. There was no evidence of vertical transmission ofCOVID-19 infection. This review critically analyzed COVID-19 as a public health hazard in order to help policy makers,health care givers, and primary physicians to promote early diagnosis and prevention.

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