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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 355 - 363 (9page)
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초록· 키워드
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Background There have been recent proposals to categorize healthcare-associated infections (HCAIs) separately from community-acquired infections (CAIs). The aim of this study was to compare the antibiotic resistance of pathogens causing CAIs, HCAIs, and hospital-acquired infections (HAIs) in Korea, and to investigate the need for different empirical antibiotics therapy for CAIs and HCAIs. Materials and Methods This prospective study was conducted in a university hospital between March and December 2019. Inpatients who underwent a bacterial culture within 2 days of hospitalization, with a Enterobacteriaceae strain identified at the infection site and available antibiotic susceptibility results, were included in the analysis. Infections were classified as CAIs, HCAIs or HAIs, depending on the source. Results Of the 146 patients included in the analysis, the prevalence of fluoroquinolone-resistant Enterobacteriaceae was 18.8%, 38.5%, and 55.0%; the prevalence of pathogens showing third-generation cephalosporins resistance was 8.3%, 50.0%, and 60.0%; and the prevalence of pathogens showing piperacillin-tazobactam resistance was 8.3%, 7.7%, 15.0% in the CAIs, HCAIs, and HAIs groups, respectively. The prevalence of extended-spectrum beta-lactamase-positive pathogens was 6.3%, 47.3%, and 55.0% in the CAIs, HCAIs, and HAIs group, respectively, with no significant difference between the HCAIs and HAIs groups. Resistance patterns of the HCAIs group more closely resembled those of the HAIs group than those of the CAIs group. Conclusion The pathogens isolated from patients with HCAIs showed resistance patterns that were more similar to those of patients with HAIs than those with CAIs. Thus, CAIs and HCAIs should be distinguished from each other when selecting antibiotic agents.
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참고문헌 (24)
참고문헌 신청
Lee H / 2018 / Antimicrobial resistance of major clinical pathogens in South Korea, May 2016 to April 2017: first one-year report from Kor-GLASS / Euro Surveill 23:1800047
Fasugba O / 2015 / Ciprofloxacin resistance in community- and hospital-acquired Escherichia coli urinary tract infections: a systematic review and meta-analysis of observational studies / BMC Infect Dis 15:545
Cardoso T / 2014 / Classification of healthcare-associated infection: a systematic review 10 years after the first proposal / BMC Med 12:40
Friedman ND / 2002 / Health care--associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections / Ann Intern Med 137:791~797
National Healthcare Safety Network (NHSN) / National Healthcare Safety Network (NHSN) patient safety component manual
Fasugba O / 2015 / Ciprofloxacin resistance in community- and hospital-acquired Escherichia coli urinary tract infections: a systematic review and meta-analysis of observational studies / BMC Infect Dis 15:545
Cardoso T / 2014 / Classification of healthcare-associated infection: a systematic review 10 years after the first proposal / BMC Med 12:40
Friedman ND / 2002 / Health care--associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections / Ann Intern Med 137:791~797
National Healthcare Safety Network (NHSN) / National Healthcare Safety Network (NHSN) patient safety component manual
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