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논문 기본 정보

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학술저널
저자정보
Jung Jiwon (Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine Seoul) Jungmin Lee (Department of Microbiology Institute for Viral Diseases Biosafety Center College of Medicine Korea) Seongmin Jo (Department of Architectural Engineering Sejong University Seoul Korea.) Bae Seongman (Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine Seoul) Ji Yeun Kim (Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine Seoul) Cha Hye Hee (Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine Seoul) Lim Young-Ju (Office for Infection Control Asan Medical Center Seoul Korea.) Kwak Sun Hee (Office for Infection Control Asan Medical Center Seoul Korea.) Hong Min Jee (Office for Infection Control Asan Medical Center Seoul Korea.) Kim Eun Ok (Office for Infection Control Asan Medical Center Seoul Korea.) Bae Joon-Yong (Department of Microbiology Institute for Viral Diseases Biosafety Center College of Medicine Korea) Kang Changmin (Department of Microbiology Institute for Viral Diseases Biosafety Center College of Medicine Korea) Sung Minki (Department of Architectural Engineering Sejong University Seoul Korea.) Park Man-Seong (Department of Microbiology Institute for Viral Diseases Biosafety Center College of Medicine Korea) Kim Sung-Han (Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine Seoul)
저널정보
대한감염학회 Infection and Chemotherapy Infection and Chemotherapy 제53권 제2호
발행연도
2021.1
수록면
332 - 341 (10page)

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Background Coronavirus disease 2019 (COVID-19) outbreaks occur in hospitals in many parts of the world. In hospital settings, the possibility of airborne transmission needs to be investigated thoroughly. Materials and Methods There was a nosocomial outbreak of COVID-19 in a hematologic ward in a tertiary hospital, Seoul, Korea. We found 11 patients and guardians with COVID-19 through vigorous contact tracing and closed-circuit television monitoring. We found one patient who probably had acquired COVID-19 through airborne-transmission. We performed airflow investigation with simulation software, whole-genome sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Results Of the nine individuals with COVID-19 who had been in the hematologic ward, six stayed in one multi-patient room (Room 36), and other three stayed in different rooms (Room 1, 34, 35). Guardian in room 35 was close contact to cases in room 36, and patient in room 34 used the shared bathroom for teeth brushing 40 minutes after index used. Airflow simulation revealed that air was spread from the bathroom to the adjacent room 1 while patient in room 1 did not used the shared bathroom. Airflow was associated with poor ventilation in shared bathroom due to dysfunctioning air-exhaust, grill on the door of shared bathroom and the unintended negative pressure of adjacent room. Conclusion Transmission of SARS-CoV-2 in the hematologic ward occurred rapidly in the multi-patient room and shared bathroom settings. In addition, there was a case of possible airborne transmission due to unexpected airflow.
#SARS-CoV-2 #COVID-19 #Hematologic malignancy #Multi-patient room #Airborne transmission

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참고문헌 (18)

참고문헌 신청
Greenhalgh T / 2021 / Ten scientific reasons in support of airborne transmission of SARS-CoV-2 / Lancet 397:1603~1605 google schola Baraniuk C / 2021 / Covid-19: What do we know about airborne transmission of SARS-CoV-2 / BMJ 373:n1030 google schola Allen JG / 2021 / Indoor air changes and potential implications for SARS-CoV-2 transmission / JAMA 325:2112~2113 google schola Samet JM / 2021 / Airborne transmission of SARS-CoV-2: what we know / Clin Infect Dis google schola Klompas M / 2021 / A SARS-CoV-2 cluster in an acute care hospital / Ann Intern Med 174:94~802 google schola

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