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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 146 - 150 (5page)
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초록· 키워드
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Acinetobacter baumannii is one of the most important etiologies of nosocomial infections in recent years mainly because of increasing in frequency of multidrug and pan-resistant pathogens. Meningitis caused by this organism is a dilemma; because polymyxins are the only effective antibiotics against pan-resistant serotypes, but have poor penetration via blood brain barrier; however, it has still remained uncertain whether the intravenous therapy with these agents is an effective treatment with the sufficient concentration of the drug in the cerebrospinal fluid. Herein, we report a neonate who suffered from pan-resistant A. baumannii nosocomial meningitis successfully treated with intravenous colistin combined with meropenem and rifampin. It seems that intravenous colistin at least in combination with rifampin and meropenem might be considered as an option to try in patients in whom daily intrathecal injection or insertion of intraventricular device is not possible.
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참고문헌 (19)
참고문헌 신청
Kim BN / 2009 / Management of meningitis due to antibiotic-resistant Acinetobacter species / Lancet Infect Dis 9:245~255
Mehar V / 2012 / Neonatal ventriculitis with multi drug resistant Acinetobacter baumanii: a case report and review of literature / Pediat Therapeut 2:1~3
Katragkou A / 2005 / Successful treatment of multidrug-resistant Acinetobacter baumannii central nervous system infections with colistin / J Clin Microbiol 43:4916~4917
Tuon FF / 2010 / Mortality rate in patients with nosocomial Acinetobacter meningitis from a Brazilian hospital / Braz J Infect Dis 14:437~440
Piparsania S / 2012 / Intraventricular polymyxin B for the treatment of neonatal meningo-ventriculitis caused by multi-resistant Acinetobacter baumannii--case report and review of literature / Turk J Pediatr 54:548~554
Mehar V / 2012 / Neonatal ventriculitis with multi drug resistant Acinetobacter baumanii: a case report and review of literature / Pediat Therapeut 2:1~3
Katragkou A / 2005 / Successful treatment of multidrug-resistant Acinetobacter baumannii central nervous system infections with colistin / J Clin Microbiol 43:4916~4917
Tuon FF / 2010 / Mortality rate in patients with nosocomial Acinetobacter meningitis from a Brazilian hospital / Braz J Infect Dis 14:437~440
Piparsania S / 2012 / Intraventricular polymyxin B for the treatment of neonatal meningo-ventriculitis caused by multi-resistant Acinetobacter baumannii--case report and review of literature / Turk J Pediatr 54:548~554
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