메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Zhong Xiaohui (Wuxi School of Medicine Jiangnan University Wuxi 214122 P.R. China) Zhang Feng (Wuxi School of Medicine Jiangnan University Wuxi 214122 P.R. ChinaClinical Assessment Center of Fun) Yin Xinyao (Wuxi School of Medicine Jiangnan University Wuxi 214122 P.R. China) Cao Hong (Clinical Assessment Center of Functional Food Affiliated Hospital of Jiangnan University Wuxi 21412) Wang Xuesong (Wuxi School of Medicine Jiangnan University Wuxi 214122 P.R. ChinaDepartment of Orthopedics Affilia) Liu Dongsong (Department of Orthopedics Affiliated Hospital of Jiangnan University Wuxi 214125 P.R.China) Chen Jing (Department of Orthopedics Affiliated Hospital of Jiangnan University Wuxi 214125 P.R.China) Chen Xue (Wuxi School of Medicine Jiangnan University Wuxi 214122 P.R. China)
저널정보
한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제31권 제6호
발행연도
2021.1
수록면
765 - 774 (10page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Although research on the osteal signaling pathway has progressed, understanding of gut microbialdependent signaling pathways for metabolic and immune bone homeostasis remains elusive. In recent years, the study of gut microbiota has shed light on our understanding of bone homeostasis. Here, we review microbiota-mediated gut?bone crosstalk via bone morphogenetic protein/SMADs, Wnt and OPG/receptor activator of nuclear factor-kappa B ligand signaling pathways in direct (translocation) and indirect (metabolite) manners. The mechanisms underlying gut microbiota involvement in these signaling pathways are relevant in immune responses, secretion of hormones, fate of osteoblasts and osteoclasts and absorption of calcium. Collectively, we propose a signaling network for maintaining a dynamic homeostasis between the skeletal system and the gut ecosystem. Additionally, the role of gut microbial improvement by dietary intervention in osteal signaling pathways has also been elucidated. This review provides unique resources from the gut microbial perspective for the discovery of new strategies for further improving treatment of bone diseases by increasing the abundance of targeted gut microbiota.

목차

등록된 정보가 없습니다.

참고문헌 (131)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0