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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 177 - 177 (1page)
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Purpose Non-invasive monitoring of brain temperature is essential for the assessment and optimization of therapeutic target temperature in acute ischemic brain. MR thermometry using 1-H MR spectroscopy (MRT) with Thulium-DOTMA (Tm-DOTMA) has the advantage of allowing absolute temperature measurements. We tried to validate MRT by comparing it with the actual brain temperature in rats. Materials and Methods Serial MRT was obtained in rats with mild systemic hypothermia (Group 1, n=5) and rats with local brain hypothermia with endovascular cooling (Group 2, n=5). Fiber optic thermometry (FOT) was inserted into the brain parenchyma to measure the actual temperature of the brain before MRT scans. For the local brain hypothermia models a 26G jelco catheter was inserted into the ICA and cold saline (4℃, 20ml) was infused in the MR bore for 20 minutes, followed by serial MRTs for 60 minutes. During MRT scans, body tem ... 전체 초록 보기
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