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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 163 - 163 (1page)
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The ingestion of supplemental human milk oligosaccharides (HMOs) is associated with a lower risk of inflammatory diseases and infections. However, whether HMOs play an important role in regulating platelet aggregation and thrombus formation remains unclear. The current study aimed to investigate the antiplatelet effect of HMOs. The antiplatelet effect of HMOs including platelet aggregation, granule secretion, calcium mobilization, and integrin activation was assessed. Moreover, its antithrombotic effect was evaluated using an in vivo mouse model of ferric chloride-induced arterial thrombus formation. The transection tail bleeding time was used to evaluate whether HMOs inhibited primary hemostasis. Among all HMOs, 2′-fucosyllactose (2′-FL) could significantly in ... 전체 초록 보기
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