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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 저널정보
- 한국수산과학회 양식분과 한국수산과학회 양식분과 학술대회 2021 Conference on the Future Technology of Fisheries Science [3개 분과 공동개최]
- 발행연도
- 2021.4
- 수록면
- 228 - 228 (1page)
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When considering the virus defence, contemporary findings suggest availability distinct interferon regulated proteins. Elucidation of mechanisms behind these proteins were shown to be beneficial for targeting specific and efficient antiviral drugs and vaccines towards pathogenic viruses. “GCHV induced gene-2 (GiG-2)” was identified from rockfish (Sebastes schlegelii). Only handful number of studies have been performed on GiG-2 due to the fact that this protein is only present in fishes and amphibians, this was a trigger to conduct this experiment. In rockfish fish revealed higher expression of both SsGiG-2-1 and SsGiG-2-2 in the gills. Organs similar to the stomach, muscles, and the liver showed weak expression. Immune challenge disclosed peak expression at 24 h of post injection for the poly I:C, indicating probable antiviral activities of GiG-2 proteins. Sequence based domain identification revealed the availability of a PARP domain region around the N-terminal ends of both proteins. In the SsGiG2-1, PARP domain spanned fr ... 전체 초록 보기
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