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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.4
- 수록면
- 556 - 556 (1page)
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이 논문의 연구 히스토리 (4)
2021
Biosynthesis of L-ergothioneine by Regulating Sulfur Assimilation in Metabolically Engineered Corynebacterium glutamicum
Minhye KIM
,
Jun Won OH
,
Hyun Jin JEONG
외 2명
한국생물공학회 학술대회
2021.10
학술대회자료
Development of Metabolically Engineered Corynebacterium glutamicum Synthesizing L-Carnosine Regarded as a Treatment of Metabolic Syndrome
Minhye KIM
,
Young Jin KO
,
Sung Ok HAN
한국생물공학회 학술대회
2021.04
학술대회자료
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L-carnosine has been regarded as a new chemotherapeutic because of its distinguishing functions. Biosynthesis of L-carnosine has been required to replace chemical process. Here, we firstly developed metabolically engineered Corynebacterium glutamicum producing L-carnosine. First, pentose phosphate pathway (PPP) was reinforced by introducing H36 promoter and attenuating flux from glucose to pyruvate. Second, histidine and β-alanine synthetic pathways were strengthened by overexpressing genes. Third, a mammalian’s carnosine synthetic pathway was introduced. Enhanced PPP increased the flux to PR ... 전체 초록 보기
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