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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.4
- 수록면
- 553 - 553 (1page)
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Heme is applied as an organic iron supplement and main ingredient in the food industry as well as pharmaceutical in medical fields. Here, we developed heme-secreting Corynebacterium glutamicum at high level by modifying cell membrane components. First, CRISPR-based recombineering was performed for the disruption of genes encoding heme binding membrane proteins. Membrane-bound heme and binding/unbinding rate were 1.20- and 1.26-fold lower in the engineered strain knocking out three heme-binding proteins (KOP strain) than the wild-type C. glutamicum, respectively. When these proteins were knocked out in the heme-overproducing strai ... 전체 초록 보기
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[HEME 02] 바다
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Metabolic Design for Phycocyanobilin Biosynthesis in Heme-Overproducing Corynebacterium glutamicum
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Enhanced biosynthesis of Organic Iron Supplement via Push and Pull Strategy in Corynebacterium glutamicum
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Combinatorial Biosynthesis Amino Acid and Iron Complement by Engineered Corynebacterium glutamicum for Food Industrial Use
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Molecular Dynamics Simulation-Based ‘Keystone Theory’ as Enhancing Cofactor-Protein Interaction in Heme Prteins
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Bio-based Production of Various Porphyrins and Derivatives in Engineered Corynebacterium glutamicum and Its Application
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Animal-free Meat Flavor Production for Vegetarian Food by Engineered Corynebacterium glutamicum
한국생물공학회 학술대회
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Corynebacterium glutamicum Uses Coproporphyrin-dependent Pathway for Heme Metabolism Instead of Protoporphyrin-dependent Branch
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Secretory Heme Production by Metabolically Engineered Escherichia coli
한국생물공학회 학술대회
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