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Targeting and Anti-cancer Activity of Conjugated Exosome in Breast Cancer
Targeting and Anti-cancer Activity of Conjugated Exosome in Breast Cancer
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.4
- 수록면
- 249 - 249 (1page)
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Targeting and Anti-cancer Activity of Conjugated Exosome in Breast Cancer
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Cancer, most cause of death in global, was able to distribute many site of human body. Especially, breast cancer had many obstacles for complete treatment because of expressing three types of receptor on their surface. Therefore, among developed various strategies of cancer-therapy, we investigated breast cancer-targeting exosomes that conjugated with curcumin possessing similar chemical structure of estrogen for binding to estrogen receptor expressed on cell membrane. Exosome, approximately 50 - 150 nm size particles that release by variety of cell types and consist of lipid bilayer involving various soluble factors such as proteins, DNA and RNA is promising drug delivery vehicles due to low immunogenicity, high bioco ... 전체 초록 보기
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