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The antioxidant activities of Korean Red Ginseng (Panax ginseng) and ginsenosides: A systemic review through in vivo and clinical trials
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Type
Academic journal
Author
Soo Kyung Park (Korea Ginseng) Sun Hee Hyun (Korea Ginseng) Gyo In (Korea Ginseng) Chae-Kyu Park (Korea Ginseng) Yi-Seong Kwak (Korea Ginseng) Young-Jin Jang (Jeonbuk National University) Bumseok Kim (Jeonbuk National University) Jong-Hoon Kim (Jeonbuk National University) Chang-Kyun Han (Korea Ginseng)
Journal
The Korean Society of Ginseng Journal of Ginseng Research Vol.45 No.1 KCI Candidated Journals SCIE
Published
2021.1
Pages
41 - 47 (7page)

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The antioxidant activities of Korean Red Ginseng (Panax ginseng) and ginsenosides: A systemic review through in vivo and clinical trials
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Abstract· Keywords

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A wide range of studies have steadily pointed out the relation of oxidative stress to the primary and secondary causes of human disease and aging. As such, there have been multiple misconceptions about oxidative stress. Most of reactive oxygen species (ROS) generated from chronic diseases cause oxidative damage to cell membrane lipids and proteins. ROS production is increased by abnormal stimulation inside and outside in the body, and even though ROS are generated in cells in response to abnormal metabolic processes such as disease, it does not mean that they directly contribute to the pathogenesis of a disease. Therefore, the focus of treatment should not be on ROS production itself but on the prevention and treatment of diseases linked to ROS production, including types 1 and 2 diabetes, cancer, heart disease, schizophrenia, Parkinson’s disease, and Alzheimer’s disease. In this regard, Korean Red Ginseng (KRG) has been traditionally utilized to help prevent and treat diseases such as diabetes, cancer, inflammation, nervous system diseases, cardiovascular disease, and hyperlipidemia. Therefore, this review was intended to summarize in vivo animal and human clinical studies on the antioxidant activities of KRG and its components, ginsenosides.
#Animal experiments #Antioxidant activities #Clinical trials #Korean Red Ginseng #Oxidative stress

Contents

ABSTRACT
1. Introduction
2. Free radicals and diseases
3. Evaluation of KRG efficacy in animal study
4. Clinical trials
5. Conclusion
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