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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.12
- 수록면
- 689 - 694 (6page)
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Strongyloidiasis is caused by Strongyloides stercoralis and is one of the most neglected tropical diseases in tropical and subtropical regions. Although several strongyloidiasis cases have been reported in Korea, genetic analysis of Korean isolates is still incomplete. In this study, a parasite was isolated from a 61-year-old man diagnosed with strongyloidiasis during the treatment of lymphoma on his retroperitoneal lymph node. Diffuse symmetric wall thickening from the ascending to descending colon and a nematode-infected intestine was observed following microscopic examination. Genomic DNA was isolated from a patient tissue block, and S. stercoralis was identified by PCR and sequencing (18S rDNA). In order to determine phylogenetic location of a Korean isolate (named KS1), we analyzed cox1 gene (500-bp) and compared it with that from 47 previous S. stercoralis isolates (28 human isolates and 19 canid isolates) from Asian countries. Our results showed that phylogenetic tree could clearly be divided into 5 different groups according to hosts and regions. KS1 was most closely related with the Chinese isolates in terms of genetic distance.
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참고문헌 (19)
참고문헌 신청
Krolewiecki A / 2019 / Strongyloidiasis : a Neglected Tropical Disease / Infect Dis Clin North Am 33:135~151
Grove DI / 1996 / Human strongyloidiasis / Adv Parasitol 38:251~309
Beknazarova M / 2016 / Strongyloidiasis : a disease of socioeconomic disadvantage / Int J Environ Res Public Health 13:517
서안나 / 2015 / Comorbid Gastric Adenocarcinoma and Gastric and Duodenal Strongyloides stercoralis Infection: A Case Report / The Korean Journal of Parasitology 53(1):95~99
Hannah Ra / 2019 / Strongyloidiasis Presenting as yellowish nodules in Colonoscopy of an Immunocompetent Patient / Clinical Endoscopy 52(1):80~82
Grove DI / 1996 / Human strongyloidiasis / Adv Parasitol 38:251~309
Beknazarova M / 2016 / Strongyloidiasis : a disease of socioeconomic disadvantage / Int J Environ Res Public Health 13:517
서안나 / 2015 / Comorbid Gastric Adenocarcinoma and Gastric and Duodenal Strongyloides stercoralis Infection: A Case Report / The Korean Journal of Parasitology 53(1):95~99
Hannah Ra / 2019 / Strongyloidiasis Presenting as yellowish nodules in Colonoscopy of an Immunocompetent Patient / Clinical Endoscopy 52(1):80~82
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