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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 12 - 19 (8page)
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초록· 키워드
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Multidrug resistance of bacteria is an emerging human health hazard and warrants development of novel antibacterial agents with more effective mode of action. Here, zinc oxide and silver nanomaterials were prepared using Ficus palmata Forssk leaf extract with efficient antibacterial activity. SEM coupled with EDS confirmed the spherical symmetry with average particle diameter 50 to 65 nm while the XRD confirmed crystalline face centered cubic structure of silver and hexagonal crystallize phase of zinc oxide nanoparticles. Antibacterial activity was evaluated for 8 pathogenic bacterial strains including 3 drug resistant pathogenic strains. The nanoparticles showed enhanced growth inhibition for resistant strains in comparison with the broad-spectrum antibiotics i.e. roxithromycin and cefixime. Minimum inhibitory concentration in μg.mL<SUP>-1</SUP> of silver nanoparticles was found to be as low as 33.3 for resistant Streptococcus haemolyticus; 11.1 for Staphylococcus aureus and E Coli; and 3.7 μg.mL<SUP>-1</SUP> for resistant Pseudomonas aeruginosa. Similarly, the minimum inhibitory concentration of zinc oxide nanoparticles was found to be 100 μg.mL<SUP>-1</SUP> against resistant Streptococcus haemolyticus and Staphylococcus aureus; 11.1 μg.mL<SUP>-1</SUP> for resistant Pseudomonas aeruginosa; and 3.7 μg.mL<SUP>-1</SUP> against resistant E coli. Ficus palmata Forssk leaf extracts can be explored effectively for synthesizing active antibacterial nanomaterials as a non-toxic and environmentally benign synthesis route.
목차
ABSTRACT
1. Introduction
2. Materials and Methods
3. Results and Discussion
4. Conclusion
References
참고문헌 (44)
참고문헌 신청
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Ashfaq M, Khan KN, Rehman MS, et al. Ecological risk assessment of pharmaceuticals in the receiving environment of pharmaceutical wastewater in Pakistan. Ecotoxicol. Environ. Saf. 2017;136:31-39.
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Al-Jassim N, Ansari MI, Harb M, Hong PY. Removal of bacterial contaminants and antibiotic resistance genes by conventional wastewater treatment processes in Saudi Arabia: is the treated wastewater safe to reuse for agricultural irrigation? Water Res. 2015;73:277-290.
Ashfaq M, Khan KN, Rehman MS, et al. Ecological risk assessment of pharmaceuticals in the receiving environment of pharmaceutical wastewater in Pakistan. Ecotoxicol. Environ. Saf. 2017;136:31-39.
Pugazhendhi A, Michael D, Prakash D, et al. Antibiogram and plasmid profiling of beta-lactamase producing multi drug resistant Staphylococcus aureus isolated from poultry litter. J. King Saud Univ. Sci. 2020;32:2723-2727.
Saravanan M, Niguse S, Abdulkader M, et al. Review on emergence of drug-resistant tuberculosis (MDR & XDR-TB) and its molecular diagnosis in Ethiopia. Microb. Pathogenesis. 2018;117:237-242.
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