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논문 기본 정보

자료유형
학술저널
저자정보
Ahmed. A. G. El-Shahawy (Beni-Suef University) Yasser GadelHak (Beni-Suef University) H. Y. Zahran (King Khalid University) I. S. Yahia (King Khalid University) S. I. El-Dek (Beni-Suef University)
저널정보
한국자기학회 Journal of Magnetics Journal of Magnetics Vol.25 No.4
발행연도
2020.12
수록면
540 - 546 (7page)
DOI
10.4283/JMAG.2020.25.4.540

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Cobalt doped magnetite Co<SUP>2+</SUP> <SUB>0.1</SUB>Fe<SUP>2+</SUP> <SUB>0.9</SUB>Fe<SUP>3+</SUP> ₂O₄ nanocrystals were synthesized chemically using simple one step coprecipitation in the absence and presence of the magnetic field. The nanocrystals were characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), magnetization studies by vibrational spectroscopy magnetometer (VSM). The signal intensity of the prepared nanoparticles was measured by magnetic resonance imaging (MRI). The cytotoxicity of the two samples versus W138 normal lung cells and AS49 lung cancer cells was investigated by MTT assay, in vitro. The TEM images showed non-spherical and aggregated nanoparticles, heterogeneously dispersed with 100 nm average size. The XRD and selected area electron diffraction of the two samples revealed good crystallinity for both samples. The room temperature magnetization curves demonstrate the general ferrimagnetic trend with a clear difference in the coercivity and the remanence keeping the saturation magnetization nearly stable. The measured MR signal intensity was well-matched with the result of the M-H loops where the sample prepared in the absence of the field was a promising T2 contrast agent. Both samples have low cytotoxicity compared to Doxorubicin.

목차

1. Introduction
2. Materials and Methods
3. Results and Discussion
4. Conclusion
References

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