지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
The diffusion cell method is the main technique employed for the in vitro diffusion test of transdermal drug delivery preparations. Most existing transdermal diffusion devices use a water bath heating structure and direct current motor magnetic stirrer. However, these devices are confronted with problems, such as large volume, incompatible vertical and horizontal diffusion cells, few diffusion cell sets, and poor reliability. To overcome these deficiencies, the system adopts a dry heating method and uses a rotating magnetic field generated by the electromagnetic stirrer to drive the magnetic stirrer. Accordingly, the resulting device is characterized by a simple structure and small volume, convenient operation, compatible vertical and horizontal diffusion cells, and numerous diffusion cell sets. The reliability and practicability of the system is verified by the in vitro percutaneous permeability test of the bisoprolol patch.
목차
ABSTRACT
1. Introduction
2. System Structure and Working Principle
3. Principle of Electromagnetic Stirring
4. System Hardware and Software
5. Experimental Result and Analysis
6. Conclusion
References
참고문헌 (11)
참고문헌 신청
Li, Y. W. / 2016 / Neuroprotective effects of a GIP analogue in the MPTP Parkinso n’s disease mouse model / Journal of the Neuropha rmacology 63(11):255~263
Tian, L. / 2012 / Research progress of transdermal diffusion test methods for transdermal drug delivery / Chinese Pharmacy 23(29):2761~2764
Wang, Y. Z / 2006 / Advances in research on oil-water partition coefficient and percutaneous absorption rate constant of Lappaconitine / Journal of Shandong University of Traditional Chinese Medicine 12(02):155~156
Li, Z. H. / 1995 / Improvement of in vitro diffusion cell in percutaneous drug administration research / China Pharmaceutical Industry Journal (07):309~643
Keshary, P. R. / 2014 / Mechanism soft tra nsdermal controlled nitroglycerin administration dev elopment of finite dosing skin permeation system 10(06):883
Tian, L. / 2012 / Research progress of transdermal diffusion test methods for transdermal drug delivery / Chinese Pharmacy 23(29):2761~2764
Wang, Y. Z / 2006 / Advances in research on oil-water partition coefficient and percutaneous absorption rate constant of Lappaconitine / Journal of Shandong University of Traditional Chinese Medicine 12(02):155~156
Li, Z. H. / 1995 / Improvement of in vitro diffusion cell in percutaneous drug administration research / China Pharmaceutical Industry Journal (07):309~643
Keshary, P. R. / 2014 / Mechanism soft tra nsdermal controlled nitroglycerin administration dev elopment of finite dosing skin permeation system 10(06):883
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