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논문 기본 정보

자료유형
학술저널
저자정보
김동명 (케이제이엠바이오) 정주영 (케이제이엠바이오) 이형곤 (케이제이엠바이오) 권용성 (케이제이엠바이오) 백진홍 (김정문알로에) 한인석 (유타대학교)
저널정보
한국생물공학회 KSBB Journal KSBB Journal Vol.35 No.3(Wn.174)
발행연도
2020.9
수록면
235 - 243 (9page)
DOI
10.7841/ksbbj.2020.35.3.235

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The objective of this study was to investigate whether extracts of aloe vera adventitious root produced by plant tissue culture technology has better effects on anti-wrinkle effect and skin-brightening than aloe vera extracts by performing in vitro assays. Aloe vera adventitious root and aloe vera were extracted by either water or 70% ethanol. Among water extract of aloe vera, water extract of aloe vera adventitious root, ethanol extract of aloe vera (AVE) and ethanol extract aloe vera adventitious root (AVRE), nitric oxide production inhibitory activity was the highest at AVRE, with a value of 62.28%. Inhibitory activities of matrix metalloproteinase (MMP)-1 and MMP-3 syntheses were highest at AVRE (65.11 and 37.21%, respectively). When analyzing synthetic activity of type I procollagen which has an antiwrinkle effect, AVRE showed higher value by 379.43% than UV-irradiated control group. The anti-melanogenic activity which correlates skin-brightening effect was also the highest at AVRE (83.77%), although, inhibitory activity of tyrosinase was not shown. Moreover, the value of DPPH radical scavenging activity of AVRE was higher than that of AVE by more than 10 times. From these results, it was confirmed that aloe vera adventitious root has better effect on wrinkle prevention and skin-brightening than aloe vera.

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Abstract
1. INTRODUCTION
2. MATERIALS AND METHODS
3. RESULTS AND DISCUSSION
4. CONCLUSION
REFERENCES

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UCI(KEPA) : I410-ECN-0101-2020-470-001290351