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논문 기본 정보
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- 학술저널
- 저자정보
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- 한국응용생명화학회 Journal of applied biological chemistry Journal of applied biological chemistry 제50권 제2호
- 발행연도
- 2007.1
- 수록면
- 74 - 77 (4page)
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Crude extracts of 69 marine organisms (27 salt marsh plants and 42 seaweeds) were screened for the inhibitory activity against the protein tyrosine phosphatase 1B (PTP1) in vitro. The most active extracts were methanol extracts from Derbesia marina (80.6% in inhibitory activity) and Symphycladia latiscula (85.6%) at the concentration of $15{\mu}g/mL$. Methanol extracts of Codium adhaerens and Hisikia fuziformis were moderately inhibitory with 71.2 and 69.1% inhibition, respectively. It was peculiar that only the extracts from seaweeds show inhibitory activity where those from salt marsh plants do not show any significant effect.
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