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논문 기본 정보

자료유형
학술저널
저자정보
Song, Hyuk (Division of Food Bioscience, RIBH, College of Biomedical & Health Science, Konkuk University) Park, Jin-Ki (National Institute of Animal Science, RDA) Kim, Hyoun Wook (National Institute of Animal Science, RDA) Lee, Won-Young (Division of Food Bioscience, RIBH, College of Biomedical & Health Science, Konkuk University)
저널정보
한국축산식품학회 한국축산식품학회지 한국축산식품학회지 제34권 제5호
발행연도
2014.1
수록면
630 - 637 (8page)

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We previously demonstrated that water-soluble egg yolk extract is not related to elevation of serum immunoglobulin E, which can initiate allergic reactions; however, it increases the level of high density lipoprotein (HDL)-cholesterol and the activity of B lymphocytes. In this study, egg white (EW) was fed to BALB/c mice to determine its influence on growth efficiency, immune modulation, and changes in serum lipid levels. A total of 50 five-wk-old BALB/c male mice were divided into 5 groups, 4 of which were fed 0, 10, 50, or 100 mg/d EW for 4 wk. Mice with an uptake of 10, 50 and 100 mg/d EW showed no significant changes in daily weight gain, feed efficiency rate, or populations of white blood cells. However, the activities of both B and T lymphocytes were significantly increased in all three EW groups at the final week of treatment. Interestingly, serum levels immunoglobulin E were not altered by EW consumption, but the IgG level was significantly increased in the 100 mg/d EW group. Serum lipid profile analyses showed no significant changes in total cholesterol, HDL, low density lipoprotein, or triglyceride levels by EW consumption. Taken together, these data demonstrate that consumption of EW promotes immune cell activities and the upregulation of serum IgG levels. However, we found no changes in serum lipid profiles and IgE levels. Therefore, our study suggests that consumption of EW might not be related to the risk of food allergy, but could be an excellent candidate for the maintenance of physiological homeostasis.

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