메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Jang, Hyun-Young (College of Animal Life Science, Kangwon National University) Kong, Hong-Sik (Dept. of Biotechnology, Genomic Engineering Center, Hankyong National University) Choi, Byoung-Yang (College of Animal Life Science, Kangwon National University) Shin, Jong-Suh (College of Animal Life Science, Kangwon National University) Cheong, Hee-Tae (School of Veterinary Medicine, Kangwon National University) Kim, Jong-Tack (School of Veterinary Medicine, Kangwon National University) Park, In-Chul (School of Veterinary Medicine, Kangwon National University) Park, Choon-Keun (College of Animal Life Science, Kangwon National University) Yang, Boo-Keun (College of Animal Life Science, Kangwon National University)
저널정보
한국동물번식학회 한국수정란이식학회지 한국수정란이식학회지 제26권 제4호
발행연도
2011.1
수록면
257 - 263 (7page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
BPA, a diphenyl compound containing groups, that make it structurally similar to synthetic estrogen and is considered as one of the major endocrine disruptors. Silymarin has extensively been used to prevent and/or alleviate some human disease, especially for the treatment of adverse liver conditions. It has an antioxidative efficacy and cancer preventive efficacy. Therefore, we examined the hypothesis that silymarin can inhibit BPA-induced toxicity in boar sperm duing in vitro storage. Sperm characteristics (motility, viability, membrane integrity and mitochondrion activity) in semen exposed to BPA (10~200 uM) were sharply lowered, while it increase in a dose and time dependent manner due to silymarin addition (50~200 uM) into semen extender in the presence of BPA (100 uM). All of the evaluated characteristics were gradually improved in the groups that were treated with silymarin (50~200 uM) in the presence of BPA (100 uM) in comparison to BPA 100 uM alone group, irrespective of incubation periods (3 and 6 h). These results demonstrate that silymarin can ameliorate the toxicity of BPA on boar sperm characteristics during in vitro storage, suggesting that silymarin indirectly act as an antioxidant.

목차

등록된 정보가 없습니다.

참고문헌 (0)

참고문헌 신청

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0