메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류
인문학
인문학 일반 역사학 철학 종교학 어문학 기타 인문학
사회과학
사회과학 일반 경영학 관광학 교육학 군사학 문헌정보학 법학 사회학 신문방송학 심리과학 정치외교학 지리학 행정학 경제학 무역학 인류학 기타 사회과학
자연과학
자연과학 일반 물리학 생물학 생활과학 수학·통계학 천문학 지구과학 화학 기타 자연과학
공학
공학 일반 건축공학 기계공학 산업공학 재료·에너지공학 전기전자공학 조선해양공학 화학공학 컴퓨터학 기타공학
의약학
의학 일반 간호학 수의학 약학 한의학 기초의학 임상의학 기타 의약학
농수해양학
농수해양학 일반 농학 수산학 식품과학 임학 축산학 해상운송학 기타 농수해양학
예술체육학
예술 일반 디자인 미술 미용 사진 음악학 의상 체육 공연매체예술 기타 예술체육학
복합학
학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

ENG

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Choi, Hyun Nam (Department of Plastic and Reconstructive Surgery, Kosin University College of Medicine) Han, Yea Sik (Department of Plastic and Reconstructive Surgery, Kosin University College of Medicine) Kim, Sin Rak (Department of Plastic and Reconstructive Surgery, Kosin University College of Medicine) Kim, Han Kyeol (Department of Plastic and Reconstructive Surgery, Kosin University College of Medicine) Kim, Hyun (Department of Anatomy, Kosin University College of Medicine) Park, Jin Hyung (Department of Plastic and Reconstructive Surgery, Kosin University College of Medicine)
저널정보
대한성형외과학회 Archives of plastic surgery : APS Archives of plastic surgery : APS 제41권 제6호
발행연도
2014.1
수록면
647 - 653 (7page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Background Administration of growth factors has been associated with increased viability of composite grafts greater than 1-cm in diameter. Platelet-rich plasma (PRP) contains many of the growth factors studied. In this study, we evaluate the effect of PRP injection on composite graft viability and the proper time for injection. Methods A total of 24 New Zealand White rabbits were divided into four groups. Autologous PRP was injected into the recipient sites three days before grafting in group 1, on the day of grafting in group 2, and three days after grafting in group 3. Group 4 served as control without PRP administration. Auricular composite grafts of 3-cm diameter were harvested and grafted back into place after being rotated 180 degrees. Median graft viability and microvessel density were evaluated at day 21 of graft via macroscopic photographs and immunofluorescent staining, respectively. Results The median graft survival rate was 97.8% in group 1, 69.2% in group 2, 55.7% in group 3, and 40.8% in the control group. The median vessel counts were 34 (per ${\times}200$ HPF) in group 1, 24.5 in group 2, 19.5 in group 3, and 10.5 in the control group. Conclusions This study demonstrates that PRP administration is associated with increased composite graft viability. All experimental groups showed a significantly higher survival rate and microvessel density, compared with the control group. Pre-administration of PRP was followed by the highest graft survival rate and revascularization. PRP treatments are minimally invasive, fast, easily applicable, and inexpensive, and offer a potential clinical pathway to larger composite grafts.
#Platelet-rich plasma #Growth substances #Tissue transplantation #Graft survival

목차

등록된 정보가 없습니다.

참고문헌 (25)

참고문헌 신청
Aden KK / 1992 / The evaluation of pharmacologic agents on composite graft survival / Arch Otolaryngol Head Neck Surg 118:175~178 google schola Brown JB / 1946 / Composite free grafts of two surfaces of skin and cartilage from the ear / Ann Surg 124:1101~1107 google schola Fann PC / 1993 / Pharmacologic and surgical enhancement of composite graft survival / Arch Otolaryngol Head Neck Surg 119:313~319 google schola Hartman DF / 1987 / Pharmacologic enhancement of composite graft survival / Arch Otolaryngol Head Neck Surg 113:720~723 google schola Chen IC / 1998 / The influence of intragraft heparin injection on the survival of composite grafts / Zhonghua Yi Xue Za Zhi (Taipei) 61:346~352 google schola

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0