Dental treatment of a patient with long QT syndrome under moderate sedation with target-controlled infusion of propofol

Kim, Kyung Jin; Hyun, Hong-Keun; Kim, Young-Jae; Kim, Jung-Wook; Shin, Teo Jeon

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자료유형: 학술저널

저자정보: Kim, Kyung Jin (Department of Pediatric Dentistry and Dental Research Institute, School of Dentistry, Seoul National University) Hyun, Hong-Keun (Department of Pediatric Dentistry and Dental Research Institute, School of Dentistry, Seoul National University) Kim, Young-Jae (Department of Pediatric Dentistry and Dental Research Institute, School of Dentistry, Seoul National University) Kim, Jung-Wook (Department of Pediatric Dentistry and Dental Research Institute, School of Dentistry, Seoul National University) Shin, Teo Jeon (Department of Pediatric Dentistry and Dental Research Institute, School of Dentistry, Seoul National University)

저널정보: 대한치과마취과학회 Journal of dental anesthesia and pain medicine Journal of dental anesthesia and pain medicine 제15권 제3호

발행연도: 2015.1

수록면: 161 - 165 (5page)

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Long QT syndrome (LQTs) is a rare congenital disorder of the heart's electrical activity. Patients with LQTs are at increased risk of developing fatal ventricular arrhythmias. Elevated levels of sympathetic stimulation can exacerbate this risk. Successful behavior management is indispensable in the treatment of patients with LQTs. However, many drugs involved in pharmacologic behavior management are known to adversely affect the QT interval. Therefore, careful selection of a sedative drug is essential in avoiding such incidences. A 10-year-old boy with a known diagnosis of LQTs required restorative treatment due to dental caries at the permanent molar. He required sedation since treatment was painful and dental phobia can trigger sympathetic stimulation, creating a dangerous situation for patients with LQTs. Therefore, the treatment was performed over two sessions under moderate sedation involving propofol combined with nitrous oxide. Restorative treatment was successful without any complications under sedation with a target-controlled infusion (TCI) of propofol. There was no significant QT prolongation during pulpal treatment. Propofol TCI may be a good candidate for sedation in patients with LQTs.

#Long QT syndrome #Moderate sedation #Propofol

참고문헌 (9)

참고문헌 신청

Shimizu W / 1991 / Differential Response of QTU Interval to Exercise, Isoproterenol, and Atrial Pacing in Patients with Congenital Long QT syndrome / Pacing Clin Electrophysiol 14:1966~1970

Hedley PL / 2009 / The genetic basis of long QT and short QT syndromes: a mutation update / Hum Mutat 30:1486~1511

Krause U / 2011 / A rare association of long QT syndrome and syndactyly:Timothy syndrome (LQT 8) / Clin Res Cardiol 100:1123~1127

Curry TB / 2006 / Acquired long QT syndrome and elective anesthesia in children / Paediatr Anaesth 16:471~478

Kies SJ / 2005 / Anesthesia for Patients with Congenital Long QT Syndrome / Anesthesiology 102:204~210

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