The Prognosis of Gastroschisis and Omphalocele

Jwa, Eunkyoung; Kim, Seong Chul; Kim, Dae Yeon; Hwang, Ji-Hee; Namgoong, Jung-Man; Kim, In-Koo

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자료유형: 학술저널

저자정보: Jwa, Eunkyoung (Department of Pediatric Surgery, Asan Medical Center, University of Ulsan College of Medicine) Kim, Seong Chul (Department of Pediatric Surgery, Asan Medical Center, University of Ulsan College of Medicine) Kim, Dae Yeon (Department of Pediatric Surgery, Asan Medical Center, University of Ulsan College of Medicine) Hwang, Ji-Hee (Department of Pediatric Surgery, Asan Medical Center, University of Ulsan College of Medicine) Namgoong, Jung-Man (Department of Pediatric Surgery, Asan Medical Center, University of Ulsan College of Medicine) Kim, In-Koo (Division of Pediatric Surgery, Department of Surgery, Gangneung Asan Hospital, University of Ulsan College of Medicine)

저널정보: 대한소아외과학회 Journal of the Korean Association of Pediatric Surgeons : JKAPS Journal of the Korean Association of Pediatric Surgeons : JKAPS 제20권 제2호

발행연도: 2014.1

수록면: 38 - 42 (5page)

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Purpose: Gastroschisis and omphalocele are major anterior abdominal wall defects. The purpose of this study was to analyze the clinical differences and mortalities of gastroschisis and omphalocele in Asan Medical Center. Methods: A retrospective review of the medical records was conducted of 103 cases of gastroschisis and omphalocele from September 1989 to February 2013 in Asan Medical Center in Korea. Results: There were 43 cases (41.7%) of gastroschisis and 60 cases (58.3%) of omphalocele. There was a female predominance in both gastroschisis (60.5%) and omphalocele (58.3%). The average gestational age at delivery was $36.7{\pm}0.4$ weeks for both groups. The mean birth weights were $2,381.9{\pm}80.6g$ for gastroschisis and $2,779.4{\pm}82.8g$ for omphalocele (p=0.001). Mean maternal ages in the gastroschisis and omphalocele groups were $27.5{\pm}0.7$ years and $30.5{\pm}0.7$ years, respectively (p=0.002). Associated malformations were documented in 13 infants (30.2%) with gastroschisis and 46 infants (76.7%) with omphalocele (p<0.001). All of gastroschisis patients except one underwent surgery including 31 primary repairs and 11 staged repairs. Fifty-two infants with omphalocele underwent surgery-primary repair in 41 infants and staged repair in 11 infants. Among 103 cases, 19 cases (18.4%) expired. Mortality rates of gastroschisis and omphalocele were 23.3% (10/43 cases) and 15.0% (9/60 cases), respectively (p=0.287). The main causes of death were abdominal compartment syndrome (6/10 cases) in gastroschisis, respiratory failure (4/9 cases) and discharge against medical advice (4/9 cases) in omphalocele. Conclusion: Gastroschisisis was associated with younger maternal age and lower birth weight than omphalocele. Associated malformations were more common in omphalocele. The mortality rates did not make a statistical significance. This might be the improvement of treatment of cardiac anomalies, because no patient died from cardiac dysfunction in our study. Furthermore, abdominal compartment syndrome might be the main cause of death in gastroschisis.

#Omphalocele #Gastroschisis #Prognosis

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Jwa, Eunkyoung

소속기관 Department of Pediatric Surgery, Asan Medical Center, University of Ulsan College of Medicine