지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Water and methanolic extracts of Ecklonia cava, a marine brown alga, were prepared by ultrasonic extraction (UE) and conventional extraction (CE) methods. The radical-scavenging activity and the inhibitory effects against hydrogen peroxide ($H_2O_2$)-induced DNA damage of the extracts were investigated. All extracts prepared by CE exhibited higher total polyphenolic content than that in the extracts prepared by UE. Extraction yield and total phenolic content increased as the UE time increased. The radical-scavenging activities increased as the UE time increased. All extracts prepared by CE exhibited higher 1,1-diphenyl-2-pricrylhydrazyl (DPPH) and hydroxyl radical-scavenging activities than did those prepared by UE. Extracts prepared by UE showed stronger scavenging activities on alkyl radical and $H_2O_2$ than those prepared by CE did. Methanolic extract with UE 12 h (100MEU-12h) and methanolic extract with CE 24 h (100MEC-24h) were selected and evaluated by comet assay for their inhibitory effect against $H_2O_2$-induced DNA damage. 100MEU-12h showed slightly greater protective effect against $H_2O_2$-induced DNA damage than 100MEC-24h. Thus, UE can be effectively used as a seaweed extraction technique, and there is potential for scale-up of the extraction process.
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참고문헌 (27)
참고문헌 신청
Adebajo, M. O. / 2001 / ESR study of alkyl radicals adsorbed on porous Vycor glass. I. Build-up of methyl and ethyl radicals / Appl. Surf. Sci 171:120~124
Ahn, G. -N. / 2007 / Antioxidant activities of phlorotannins purified from Ecklonia cava on free radical scavenging using ESR and H2O2-mediated DNA damage / Eur. Food Res. Technol 226:71~79
Ahn, M. -J. / 2004 / Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava / Biol. Pharm. Bull 27:544~547
Albu, S. / 2004 / Potential for the use of ultrasound in the extraction of antioxidants from Rosmarinus officinalis for the food and pharmaceutical industry / Ultrason. Sonochem 11:261~265
Chandler, S. F. / 1983 / The effect of phosphate, nitrogen and sucrose on the production of phenolics and solasodine in callus cultures of Solanum laciniatum / Plant Cell Rep 2:205~208
Ahn, G. -N. / 2007 / Antioxidant activities of phlorotannins purified from Ecklonia cava on free radical scavenging using ESR and H2O2-mediated DNA damage / Eur. Food Res. Technol 226:71~79
Ahn, M. -J. / 2004 / Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava / Biol. Pharm. Bull 27:544~547
Albu, S. / 2004 / Potential for the use of ultrasound in the extraction of antioxidants from Rosmarinus officinalis for the food and pharmaceutical industry / Ultrason. Sonochem 11:261~265
Chandler, S. F. / 1983 / The effect of phosphate, nitrogen and sucrose on the production of phenolics and solasodine in callus cultures of Solanum laciniatum / Plant Cell Rep 2:205~208
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