지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Adjuvants are immune enhancers that are often used in vaccination to augment the immune response of a vaccine, thereby enhancing the protective immunity against the targeted disease. In the present study, we used the recombinant protein, such as rRbCC1, this protein was produced from rock bream CC chemokine 1. To verify the adjuvant effects of this recombinant protein, the immune responses of rock bream to Streptococcus iniae (S. iniae) FKC vaccination, which alone or in combination with recombinant protein was analyzed and then also performed experimental challenge with live S. iniae. The result of serum agglutination titres was showed relatively low levels however, the efficacy of FKC vaccine still conferred protection against S. iniae. Moreover, the adverse effects result showed that no statistically significant difference was revealed between high concentration injected and non-injected fish groups, generally. The relative percent survival (RPS) of FKC + recombinant vaccination group was significantly higher than that of vaccinated group with FKC alone. After experimental challenge to the rock bream by injection with live bacteria (S. iniae), the FKC + rRbCC1 vaccination group was showed 87.0% RPS, however, the RPS of FKC alone vaccination was 68.2%. The results indicated that the recombinant protein as an adjuvant had a clear synergism to injection vaccine of rock bream.
목차
등록된 정보가 없습니다.
참고문헌 (33)
참고문헌 신청
Aakre, R. / 1994 / Enhanced antibody response in Atlantic salmon (Salmo salar L.) to Aeromonas salmonicida cell wall antigens using a bacterin containing β- 1,3-M-glucan as adjuvant / Fish Shellfish Immunol 4:47~61
Agnew, W. / 2007 / Streptococcus iniae : an aquatic pathogen of global veterinary significance and a challenging candidate for reliable vaccination / Vet. Microbiol 122:1~15
Altman, A. / 1989 / Immunomodifiers in vaccines / Adv. Vet. Sci. Comp. Med 23:301~341
Se Chang Park / 2006 / Isolation and characterization of Streptococcus sp.from diseased flounder (Paralichthys olivaceus )in Jeju Island / Journal of Veterinary Science 7(1):53~58
Bercovier, H. / 1997 / Immunization with bacterial antigens : infections with streptococci and related organisms / Dev. Biol. Stand 90:153~160
Agnew, W. / 2007 / Streptococcus iniae : an aquatic pathogen of global veterinary significance and a challenging candidate for reliable vaccination / Vet. Microbiol 122:1~15
Altman, A. / 1989 / Immunomodifiers in vaccines / Adv. Vet. Sci. Comp. Med 23:301~341
Se Chang Park / 2006 / Isolation and characterization of Streptococcus sp.from diseased flounder (Paralichthys olivaceus )in Jeju Island / Journal of Veterinary Science 7(1):53~58
Bercovier, H. / 1997 / Immunization with bacterial antigens : infections with streptococci and related organisms / Dev. Biol. Stand 90:153~160
이 논문의 저자 정보
최근 본 자료
댓글(0)
0