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학술저널
저자정보
Bedair, Tarek M. (Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology) Cho, Youngjin (Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology) Park, Bang Ju (Department of Electronic Engineering & Institute of Gachon Fusion Technology, Gachon University) Joung, Yoon Ki (Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology) Han, Dong Keun (Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology)
저널정보
테크노프레스 Biomaterials and biomedical engineering Biomaterials and biomedical engineering 제1권 제3호
발행연도
2014.1
수록면
131 - 150 (20page)

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Vascular stenting has a great attention as a treatment for coronary arteries diseases as compared with percutaneous balloon angioplasty. In-stent restenosis and thrombosis are side effects resulting from using bare metal stent (BMS). Employing platelet therapy allowed to reduce the rate of thrombosis, however, the rate of restenosis remains a major problem. In 2002, drug-eluting stents (DESs) were introduced as an effort to reduce the restenosis. The commercially available DESs continue to suffer from coating defects that might lead to a series of adverse effects. Most importantly, multiple concerns remain regarding the polymer coating integrity on metal surfaces or the relation of polymer irregularities to longterm adverse events.

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