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논문 기본 정보

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학술저널
저자정보
Zhou, Hang (Department of Obstetrics and Gynecology, Tongji Hospital) Li, Xiong (Department of Obstetrics and Gynecology, Tongji Hospital) Zhang, Yuan (Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology) Jia, Yao (Department of Obstetrics and Gynecology, Tongji Hospital) Hu, Ting (Department of Obstetrics and Gynecology, Tongji Hospital) Yang, Ru (Department of Obstetrics and Gynecology, Tongji Hospital) Huang, Ke-Cheng (Department of Obstetrics and Gynecology, Tongji Hospital) Chen, Zhi-Lan (Department of Obstetrics and Gynecology, Tongji Hospital) Wang, Shao-Shuai (Department of Obstetrics and Gynecology, Tongji Hospital) Tang, Fang-Xu (Department of Obstetrics and Gynecology, Tongji Hospital) Zhou, Jin (Department of Obstetrics and Gynecology, Tongji Hospital) Chen, Yi-Le (Department of Gynecologic Neoplasms, Hunan Province Tumor Hospital, The Affiliated Tumor Hospital of Central South University) Wu, Li (Department of Gynecologic Neoplasms, Hunan Province Tumor Hospital, The Affiliated Tumor Hospital of Central South University) Han, Xiao-Bing (The First Affiliated Hosp) Lin, Zhong-Qiu Lu, Xiao-Mei Xing, Hui Qu, Peng-Peng Cai, Hong-Bing Song, Xiao-Jie Tian, Xiao-Yu Zhang, Qing-Hua Shen, Jian Liu, Dan Wang, Ze-Hua Xu, Hong-Bing Wang, Chang-Yu Xi, Ling Deng, Dong-Rui Wang, Hui Lv, Wei-Guo Shen, Keng Wang, Shi-Xuan Xie, Xing Cheng, Xiao-Dong Ma, Ding Li, Shuang
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제16권 제9호
발행연도
2015.1
수록면
3,773 - 3,777 (5page)

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Background: This study aimed to establish a nomogram by combining clinicopathologic factors with overall survival of stage IA-IIB cervical cancer patients after complete resection with pelvic lymphadenectomy. Materials and Methods: This nomogram was based on a retrospective study on 1,563 stage IA-IIB cervical cancer patients who underwent complete resection and lymphadenectomy from 2002 to 2008. The nomogram was constructed based on multivariate analysis using Cox proportional hazard regression. The accuracy and discriminative ability of the nomogram were measured by concordance index (C-index) and calibration curve. Results: Multivariate analysis identified lymph node metastasis (LNM), lymph-vascular space invasion (LVSI), stromal invasion, parametrial invasion, tumor diameter and histology as independent prognostic factors associated with cervical cancer survival. These factors were selected for construction of the nomogram. The C-index of the nomogram was 0.71 (95% CI, 0.65 to 0.77), and calibration of the nomogram showed good agreement between the 5-year predicted survival and the actual observation. Conclusions: We developed a nomogram predicting 5-year overall survival of surgically treated stage IA-IIB cervical cancer patients. More comprehensive information that is provided by this nomogram could provide further insight into personalized therapy selection.

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