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논문 기본 정보

자료유형
학술저널
저자정보
Motono, Nozomu (Department of Thoracic Surgery, Kanazawa Medical University) Ueno, Masakatsu (Department of Thoracic Surgery, Kanazawa Medical University) Tanaka, Makoto (Department of Thoracic Surgery, Kanazawa Medical University) Machida, Yuichiro (Department of Thoracic Surgery, Kanazawa Medical University) Usuda, Katsuo (Department of Thoracic Surgery, Kanazawa Medical University) Sakuma, Tsutomu (Department of Thoracic Surgery, Kanazawa Medical University) Sagawa, Motoyasu (Department of Thoracic Surgery, Kanazawa Medical University)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제23호
발행연도
2014.1
수록면
10,171 - 10,174 (4page)

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Background: The purpose of this study was to determine the prognostic significance of the maximum standardized uptake value (SUVmax) on F-18-fluorodeoxyglucose (FDG)-positron emission tomography (PET) in patients undergoing surgical treatment for non-small cell lung cancer. Materials and Methods: Seventy-eight consecutive patients (58 with adenocarcinomas, 20 with squamous cell carcinomas) treated with potentially curative surgery were retrospectively reviewed. Results: The SUVmax was significantly higher in the patients with recurrent than with non-recurrent adenocarcinoma (p<0.01). However, among the patients with squamous cell carcinoma, there were no differences with or without recurrence (p=0.69). Multivariate analysis indicated that the SUVmax of adenocarcinoma lesions was a significant predictor of disease-free survival (p=0.04). In addition, an SUVmax of 6.19, the cut-off point based on ROC curve analysis of the patients with pathological IB or more advanced stage adenocarcinomas, was found to be a significant predictor of disease-free survival (p<0.01). Conclusions: SUVmax is a useful predictor of disease-free survival in patients with resected adenocarcinoma, but not squamous cell carcinoma. Patients with adenocarcinoma exhibiting an SUVmax above 6.19 are candidates for more intensive adjuvant therapy.

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