Differentiation of Benign from Malignant Adnexal Masses by Functional 3 Tesla MRI Techniques: Diffusion-Weighted Imaging and Time-Intensity Curves of Dynamic Contrast-Enhanced MRI

Malek, Mahrooz; Pourashraf, Maryam; Mousavi, Azam Sadat; Rahmani, Maryam; Ahmadinejad, Nasrin; Alipour, Azam; Hashemi, Firoozeh Sadat; Shakiba, Madjid

추천

검색

자료유형: 학술저널

저자정보: Malek, Mahrooz (Department of Radiology, Medical Imaging Center, Advanced Diagnostic and Interventional Radiology Research Center [ADIR], Imam Khomeini Hospital) Pourashraf, Maryam (Department of Radiology, Medical Imaging Center, Advanced Diagnostic and Interventional Radiology Research Center [ADIR], Imam Khomeini Hospital) Mousavi, Azam Sadat (Department of Gynecology Oncology, Vali-e-Asr Hospital, Tehran University of Medical Sciences) Rahmani, Maryam (Department of Radiology, Medical Imaging Center, Advanced Diagnostic and Interventional Radiology Research Center [ADIR], Imam Khomeini Hospital) Ahmadinejad, Nasrin (Department of Radiology, Medical Imaging Center, Advanced Diagnostic and Interventional Radiology Research Center [ADIR], Imam Khomeini Hospital) Alipour, Azam (Department of Radiology, Medical Imaging Center, Advanced Diagnostic and Interventional Radiology Research Center [ADIR], Imam Khomeini Hospital) Hashemi, Firoozeh Sadat (Department of Gynecology Oncology, Vali-e-Asr Hospital, Tehran University of Medical Sciences) Shakiba, Madjid (Department of Radiology, Medical Imaging Center, Advanced Diagnostic and)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제16권 제8호

발행연도: 2015.1

수록면: 3,407 - 3,412 (6page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Background: The aim of this study was to evaluate and compare the accuracy of diffusion-weighted imaging (DWI), apparent diffusion coefficient (ADC) value, and time-intensity curve (TIC) type analysis derived from dynamic contrast-enhanced MR imaging (DCE-MRI) in differentiating benign from malignant adnexal masses. Materials and Methods: 47 patients with 56 adnexal masses (27 malignant and 29 benign) underwent DWI and DCE-MRI examinations, prior to surgery. DWI signal intensity, mean ADC value, and TIC type were determined for all the masses. Results: High signal intensity on DWI and type 3 TIC were helpful in differentiating benign from malignant adnexal masses (p<0.001). The mean ADC value was significantly lower in malignant adnexal masses (p<0.001). An ADC value< $1.20{\times}10^{-3}mm^2/s$ may be the optimal cutoff for differentiating between benign and malignant tumors. The negative predictive value for low signal intensity on DWI, and type 1 TIC were 100%. The pairwise comparison among the receiver operating characteristic (ROC) curves showed that the area under the curve (AUC) of TIC was significantly larger than the AUCs of DWI and ADC (p<0.001 for comparison of TIC and DWI, p<0.02 for comparison of TIC and ADC value). Conclusions: DWI, ADC value and TIC type derived from DCE-MRI are all sensitive and relatively specific methods for differentiating benign from malignant adnexal masses. By comparing these functional MR techniques, TIC was found to be more accurate than DWI and ADC.

#Adnexal mass #diffusion-weighted imaging #apparent diffusion coefficient #dynamic contrast-enhanced MRI

참고문헌 (0)

참고문헌 신청

참고문헌이 DBpia에서 서비스 중이라면, [참고문헌 신청]을 통해 등록해보세요

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

Malek, Mahrooz

소속기관 Department of Radiology, Medical Imaging Center, Advanced Diagnostic and Interventional Radiology Re