Adjuvant Radiotherapy after Breast Conserving Treatment for Breast Cancer:A Dosimetric Comparison between Volumetric Modulated Arc Therapy and Intensity Modulated Radiotherapy

Liu, Zhe-Ming; Ge, Xiao-Lin; Chen, Jia-Yan; Wang, Pei-Pei; Zhang, Chi; Yang, Xi; Zhu, Hong-Cheng; Liu, Jia; Qin, Qin; Xu, Li-Ping; Lu, Jing; Zhan, Liang-Liang; Cheng, Hong-Yan; Sun, Xin-Chen

추천

검색

자료유형: 학술저널

저자정보: Liu, Zhe-Ming (Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University) Ge, Xiao-Lin (Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University) Chen, Jia-Yan (Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University) Wang, Pei-Pei (Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University) Zhang, Chi (Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University) Yang, Xi (Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University) Zhu, Hong-Cheng (Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University) Liu, Jia (Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University) Qin, Qin (Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University) Xu, Li-Ping (Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University) Lu, Jing (Department of Radiation Oncology, The Fi) Zhan, Liang-Liang Cheng, Hong-Yan Sun, Xin-Chen

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제16권 제8호

발행연도: 2015.1

수록면: 3,257 - 3,265 (9page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Background: Radiotherapy is an important treatment of choice for breast cancer patients after breast-conserving surgery, and we compare the feasibility of using dual arc volumetric modulated arc therapy (VMAT2), single arc volumetric modulated arc therapy (VMAT1) and Multi-beam Intensity Modulated Radiotherapy (M-IMRT) on patients after breast-conserving surgery. Materials and Methods: Thirty patients with breast cancer (half right-sided and half left-sided) treated by conservative lumpectomy and requiring whole breast radiotherapy with tumor bed boost were planned with three different radiotherapy techniques: 1) VMAT1; 2) VMAT2; 3) M-IMRT. The distributions for the planning target volume (PTV) and organs at risk (OARs) were compared. Dosimetries for all the techniques were compared. Results: All three techniques satisfied the dose constraint well. VMAT2 showed no obvious difference in the homogeneity index (HI) and conformity index (CI) of the PTV with respect to M-IMRT and VMAT1. VMAT2 clearly improved the treatment efficiency and can also decrease the mean dose and V5Gy of the contralateral lung. The mean dose and maximum dose of the spinal cord and contralateral breast were lower for VMAT2 than the other two techniques. The very low dose distribution (V1Gy) of the contralateral breast also showed great reduction in VMAT2 compared with the other two techniques. For the ipsilateral lung of right-sided breast cancer, the mean dose was decreased significantly in VMAT2 compared with VMAT1 and M-IMRT. The V20Gy and V30Gy of the ipsilateral lung of the left-sided breast cancer for VMAT2 showed obvious reduction compared with the other two techniques. The heart statistics of VMAT2 also decreased considerably compared to VMAT1 and M-IMRT. Conclusions: Compared to the other two techniques, the dual arc volumetric modulated arc therapy technique reduced radiation dose exposure to the organs at risk and maintained a reasonable target dose distribution.

#Breast cancer #VMAT #IMRT #dosimetry #DVH

참고문헌 (0)

참고문헌 신청

참고문헌이 DBpia에서 서비스 중이라면, [참고문헌 신청]을 통해 등록해보세요

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

Liu, Zhe-Ming

소속기관 Department of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University