Role of PET/CT in Treatment Planning for Head and Neck Cancer Patients Undergoing Definitive Radiotherapy

Arslan, Sonay; Abakay, Candan Demiroz; Sen, Feyza; Altay, Ali; Akpinar, Tayyar; Ekinci, Ahmet Siyar; Esbah, Onur; Uslu, Nuri; Kekilli, Kezban Esra; Ozkan, Lutfi

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자료유형: 학술저널

저자정보: Arslan, Sonay (Department of Radiation Oncology, Diyarbakir Gazi Yasargil Education and Research Hospital) Abakay, Candan Demiroz (Department of Radiation Oncology, Uludag University, Faculty of Medicine) Sen, Feyza (Department of Nuclear Medicine, Uludag University, Faculty of Medicine) Altay, Ali (Department of Radiation Oncology, Uludag University, Faculty of Medicine) Akpinar, Tayyar (Department of Nuclear Medicine, Uludag University, Faculty of Medicine) Ekinci, Ahmet Siyar (Department of Medical Oncology, Diyarbakir Gazi Yasargil Education and Research Hospital) Esbah, Onur (Department of Medical Oncology, Diyarbakir Gazi Yasargil Education and Research Hospital) Uslu, Nuri (Department of Radiation Oncology, Diyarbakir Gazi Yasargil Education and Research Hospital) Kekilli, Kezban Esra (Department of Radiation Oncology, Bursa Ali Osman Sonmez Oncology Hospital) Ozkan, Lutfi (Department of Radiation Oncology, Uludag University, Faculty of Medicine)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제24호

발행연도: 2014.1

수록면: 10,899 - 10,903 (5page)

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Background: In this study, we aimed to investigate the benefits of 18F-deoxyglucose positron emission tomography/computed tomography (FGD-PET/CT) imaging for staging and radiotherapy planning in patients with head and neck cancer undergoing definitive radiotherapy. Materials and Methods: Thirty-seven head and neck cancer patients who had undergone definitive radiotherapy and PET/CT at the Uludag University Medical Faculty Department of Radiation Oncology were investigated in order to determine the role of PET/CT in staging and radiotherapy planning. Results: The median age of this patient group of 32 males and 5 females was 57 years (13-84years). The stage remained the same in 18 cases, decreased in 5 cases and increased in 14 cases with PET/CT imaging. Total gross tumor volume (GTV) determined by CT (GTVCT-Total) was increased in 32 cases (86.5%) when compared to total GTV determined by PET/CT (GTVPET/CT-Total). The GTV of the primary tumor determined by PET/CT (GTVPET/CT) was larger in 3 cases and smaller in 34 cases compared to that determined by CT (GTVCT). The GTV of lymph nodes determined by PET/CT (GTVLNPET/CT) was larger in 20 cases (54%) and smaller in 12 cases (32.5%) when compared to GTV values determined by CT (GTVLNCT). No pathological lymph nodes were observed in the remaining five cases with both CT and PET/CT. Conclusions: We can conclude that PET/CT can significantly affect both pretreatment staging and assessed target tumor volume in patients with head and neck cancer. We therefore recommend examining such cases with PEC/CT before treatment.

#Head and neck cancer #PET-CT #radiotherapy

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