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자료유형
학술저널
저자정보
Sadighi, Sanambar (Department of Internal Medicine, Cancer Research Center, Tehran University of Medical Sciences) Roshanaee, Ghodratollah (Biostatistics Department, Hamadan University of Medical Sciences) Vahedi, Saba (Department of Internal Medicine, Cancer Research Center, Tehran University of Medical Sciences) Jahanzad, Easa (Department of Pathology, Cancer Research Center, Tehran University of Medical Sciences) Mohagheghi, Mohammad Ali (Department of Surgical Oncology, Cancer Research Center, Tehran University of Medical Sciences) Mousavi-Jarahi, Alireza (Department of Social Medicine, Shahid Beheshti University of Medical Sciences)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제18호
발행연도
2014.1
수록면
7,835 - 7,838 (4page)

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Background: Neuroendocrine tumors have widespread and different clinical presentations and prognoses. This study was conducted to assess their survival time and prognostic factors in Iran. Materials and Methods: In a retrospective cohort study, 189 patients diagnosed of having neuroendocrine carcinoma were chosen. The tumor and clinical characteristics of the patients were modeled with a Cox proportional hazard approach. Survival was assessed using Kaplan-Meyer curves. Results: Crude median survival time was 30 months. Women survived longer than men (the median survival time for women was 40 and for men was 24 months). Age (<60 vs >60 years old with hazard ratio (HR) of 2.43, 95% CI 1.3-4.5), primary pathology report (carcinoid vs. others with HR 5.85 cm, 95% CI 2.4-14.3), tumor size cm (for 5-10, HR of 3.1, 95% CI 1.6 and for >10 HR of 8.2, 95% with 95% CI 3.1-21.9), and chemotherapy with single drug (taking vs. not taking with a HR 2.2, 95% CI 1.1-4.8) had significant effects on overall survival of patients. Conclusions: Survival time in patients with neuroendocrine carcinomas is related to demographics, clinical characteristics, tumor histology, and subtype specific treatment.

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