Incidence and Clinical Outcomes of Non-endometrioid Carcinoma of Endometrium: Siriraj Hospital Experience

Jaishuen, Atthapon; Kunakornporamat, Kate; Viriyapak, Boonlert; Benjapibal, Mongkol; Chaopotong, Pattama; Petsuksiri, Janjira; Therasakvichya, Suwanit

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저자정보: Jaishuen, Atthapon (Department of Obstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University) Kunakornporamat, Kate (Department of Obstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University) Viriyapak, Boonlert (Department of Obstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University) Benjapibal, Mongkol (Department of Obstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University) Chaopotong, Pattama (Department of Obstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University) Petsuksiri, Janjira (Department of Radiology, Faculty of Medicine, Siriraj Hospital, Mahidol University) Therasakvichya, Suwanit (Department of Obstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제6호

발행연도: 2014.1

수록면: 2,905 - 2,909 (5page)

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Background: To study the incidence of non-endometrioid carcinoma of endometrium and compare the clinical characteristics and treatment outcomes with endometrioid carcinoma patients. Materials and Methods: This study included 236 patients with endometrial carcinoma at Siriraj Hospital whom were diagnosed and treated from 2003 through 2006. The clinical characteristics, pathological features, treatment and clinical outcomes were collected from the medical records. The 5-year survival was calculated according to 2009 FIGO staging. Results: Non-endometrioid carcinoma of endometrium accounted for 10.2% of all endometrial carcinomas (24/236 patients). The 5-year survival rate was significantly lower in the non-endometrioid group compared to the endometrioid group (77.3% vs 96%, p<0.001) and clinical data pointed to greater malignancy. Conclusions: Non-endometrioid carcinoma of endometrium is relative rare but is more aggressive, has more distant metastasis at diagnosis with a worse survival rate than endometrioid carcinoma. Only patients in stage IA with no residual disease on a hysterectomy specimen may not need adjuvant treatment.

#Endometrial carcinoma #non-endometrioid #survival outcome #distant metastasis

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Jaishuen, Atthapon

소속기관 Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University