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논문 기본 정보

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학술저널
저자정보
Mansour-Ghanaei, Fariborz (Gastrointestinal and Liver Diseases Research Center [GLDRC], Guilan University of Medical Sciences) Joukar, Farahnaz (Gastrointestinal and Liver Diseases Research Center [GLDRC], Guilan University of Medical Sciences) Rajpout, Yaghoub (Internal Medicine Department, Jahrom University of Medical Sciences) Hasandokht, Tolou (Community Medicine Department, Guilan University of Medical Sciences)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제18호
발행연도
2014.1
수록면
7,635 - 7,638 (4page)

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Background: The aim of this study was to investigate the value of serum gastric markers to differentiate between patients with precancerous lesions and nonatrophic chronic gastritis. Materials and Methods: Serum samples of 128 patients with dyspepsia who were candidates for endoscopic examination were tested for pepsinogen (PG I and PG II), PG I/II ratio, gastrin 17(G-17), anti-Helicobacter pylori (anti-H pylori ) and anti-CagA antibodies. Two sample t-tests, chi-square tests and Pearson's correlation analyses were used for analysis using SPSS (version 20). Results: PGI, PG I/II ratio values were decreased significantly in the precancerous lesion group (0.05, 0.001 respectively). The frequency of H pylori infection was significantly (p=0.03) different between the two groups ofthe study. Conclusions: We suggest PGI and the PG I/II ratio as valuable markers for screening of premalignant gastric lesions.

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