Cancer: Scenario and Relationship of Different Geographical Areas of the Globe with Special Reference to North East-India

Sharma, Jagannath Dev; Kalit, Manoj; Nirmolia, Tulika; Saikia, Sidhartha Protim; Sharma, Arpita; Barman, Debanjana

추천

검색

자료유형: 학술저널

저자정보: Sharma, Jagannath Dev (Population Based Cancer Registry, Indian Council of Medical Research, Dr. B. Borooah Cancer Institute) Kalit, Manoj (Population Based Cancer Registry, Indian Council of Medical Research, Dr. B. Borooah Cancer Institute) Nirmolia, Tulika (Department of Biotechnology, Assam Medical College and Hospital) Saikia, Sidhartha Protim (Department of Biotechnology, Assam Medical College and Hospital) Sharma, Arpita (Population Based Cancer Registry, Indian Council of Medical Research, Dr. B. Borooah Cancer Institute) Barman, Debanjana (Population Based Cancer Registry, Indian Council of Medical Research, Dr. B. Borooah Cancer Institute)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제8호

발행연도: 2014.1

수록면: 3,721 - 3,729 (9page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Background: Cancer is becoming the most important public health burden around the globe. As per the GLOBOCAN 2008 estimates, about 12.7 million cancer cases and 7.6 million cancer deaths were estimated to have occurred in 2008. The burden of cancer cases for India in the year 2020 is calculated to be 1,148,757 (male 534,353; female 614,404) compared to 979,786 in 2010. The pattern of cancer incidence is varying among geographical regions, esophageal cancer for example being high in China, lung cancer in USA, and gallbladder cancer in Chile. The question remains why? Is it due to the diversity in genome pool, food habits, risk factor association and role of genetic susceptibility or some other factors associated with it? In India, the North East (NE)-India region is seeing a marked increase in cancer incidence and deaths, with a very different cancer incidence pattern compared to mainland India. The genome pool of the region is also quite distinct from the rest of India. Northeastern tribes are quite distinct from other groups; they are more closely related to East Asians than to other Indians. In this paper an attempt was made to see whether there is any similarity among the pattern of cancer incidence cases for different sites of NE-India region to South or East-Asia. Materials and Methods: Principal Component Analysis (PCA), Hierarchical Cluster Analysis (HCA), Pearson Correlation coefficient test was assessed to evaluate the linkage of North-East India region to other regions. A p value <0.05 was considered as statistically significant. Results: The results clearly shows that there are similarities in occurrence of cancer incidence patterns for various cancer sites of NE-India with South and East-Asian regions, which may lead to the conclusion that there might be a genetic linkage between these regions.

#Cancer #oesophagus #lung #stomach #hypopharynx #nasopharynx #TRC

참고문헌 (0)

참고문헌 신청

참고문헌이 DBpia에서 서비스 중이라면, [참고문헌 신청]을 통해 등록해보세요

이 논문의 저자 정보

Sharma, Jagannath Dev

소속기관 Department of Cancer Registry, Epidemiology and Biostatistics, Dr.B Borooah Cancer Institute