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논문 기본 정보

자료유형
학술저널
저자정보
Varol, Umut (Medical Oncology Clinic, Izmir Katip Celebi University Ataturk Training and Research Hospital) Yildiz, Ibrahim (Medical Oncology Clinic, Izmir Katip Celebi University Ataturk Training and Research Hospital) Alacacioglu, Ahmet (Medical Oncology Clinic, Izmir Katip Celebi University Ataturk Training and Research Hospital) Uslu, Ruchan (Division of Medical Oncology, Tulay Aktas Oncology Hospital, School of Medicine, Ege University)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제4호
발행연도
2014.1
수록면
1,885 - 1,887 (3page)

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Skin metastases of breast cancer are usually late events in the course of tumor progression and signify a poor prognosis. They may remain as a therapeutic challenge especially after failure of standard treatments. Topical interventions, together with or without radiotherapy, may only palliate the symptoms temporarily. However, there may be alternative treatment modalities for unresectable breast cancer skin metastases resistant to chemotherapy and radiotherapy. There are various genetic alterations in tumors and therapeutic potential of expression patterns for factors like epidermal growth factor receptor may have important clinical implications in case of disease refractory to the conventional treatments. Here, we clarified the therapeutic options and genetic alterations in skin metastatic breast cancer patients refractory to standard chemotherapeutics.

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