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논문 기본 정보

자료유형
학술저널
저자정보
Demir, Nalan (Department of Chest Diseases, Faculty of Medicine, Ankara University) Enon, Serkan (Department of Thoracic Surgery, Faculty of Medicine, Ankara University) Turksoy, Vugar Ali (Institute of Forensic Sciences, Ankara University) Kayaalti, Zeliha (Institute of Forensic Sciences, Ankara University) Kaya, Seda (Institute of Forensic Sciences, Ankara University) Cangir, Ayten Kayi (Department of Thoracic Surgery, Faculty of Medicine, Ankara University) Soylemezoglu, Tulin (Institute of Forensic Sciences, Ankara University) Savas, Ismail (Department of Chest Diseases, Faculty of Medicine, Ankara University)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제7호
발행연도
2014.1
수록면
2,965 - 2,970 (6page)

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Background: To evaluate association of lung cancer with arsenic and cadmium levels measured in tumor tissue. Materials and Methods: Ninety-five patients with lung cancer tumor tissue obtained surgically were included in this study. Arsenic and cadmium levels were measured and levels of metals were compared among types of lung cancer and with reference to patient data. Results: The histopathologic diagnoses of the 95 cases were SCC, 49, adenocarcinoma, 28, large cell, 11 and SCLC, 1. Mean tumor arsenic and cadmium levels were $149.3{\pm}129.1{\mu}g/kg$ and $276.3{\pm}219.3{\mu}g/kg$, respectively. Cadmium levels were significantly associated with smoking (p=0.02), histopathologic type (p=0.005), and TNM staging (r=0.325; p=0.001), although arsenic was not related to any parameter (p>0.05). There was no relation between metal levels and mortality (p>0.05). Conclusions: We found a significant association between tumor cadmium levels of patients with lung cancer and smoking, histopathologic type and staging, although there was no relation with arsenic levels.

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