Correlation of Habits and Clinical Findings with Histopathological Diagnosis in Oral Submucosal Fibrosis Patients

Ara, Syeda Arshiya; Arora, Vini; Zakaullah, Syed; Raheel, Syed Ahmed; Rampure, Prakash; Ashraf, Sajna

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자료유형: 학술저널

저자정보: Ara, Syeda Arshiya (Department of Oral Medicine and Radiology, Al-Badar Rural Dental College and Hospital) Arora, Vini (Department of Oral Medicine and Radiology, Al-Badar Rural Dental College and Hospital) Zakaullah, Syed (Department of Oral and Maxillofacial Surgery, Al-Badar Rural Dental College and Hospital) Raheel, Syed Ahmed (Department of Oral Medicine and Radiology, Al-Badar Rural Dental College and Hospital) Rampure, Prakash (Department of Oral Medicine and Radiology, Al-Badar Rural Dental College and Hospital) Ashraf, Sajna (Department of Oral Medicine and Radiology, Al-Badar Rural Dental College and Hospital)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제14권 제12호

발행연도: 2013.1

수록면: 7,075 - 7,080 (6page)

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Background: Oral submucosal fibrosis (OSMF) is one of the most prevalent premalignant conditions in India which is easy to diagnose but difficult to manage. At present it is considered as irreversible and incurable. It has also been referred to as an epidemic in India. Aims and Objectives: To correlate the frequency and duration of habits with clinical staging, functional staging and histopathological grading and to correlate the clinical and functional staging with histopathological grading. Materials and Methods: The study included a total of 90 subjects, 80 with OSMF in the experimental group and 10 patients in the control group. Patient personal history was recorded with chewing habits, including frequency and duration of chewing. The site of keeping the quid, time duration and whether he/she swallows it or spits it were also noted. Clinical staging was done on the presence of palpable fibrous bands. Functional staging was accomplished by measuring mouth opening. Incisional biopsy was done for all the patients for histopathological examination. Histopathological grading was according to Pindborg and Sirsat. Results: The experimental group comprised 71 males and 9 females, the majority of which were in the age group of 21-30 years. Correlation of habits with clinical staging, functional staging and histopathological grading were significant (p<0.05). Clinical and functional staging did not correlate with histopathological grading, but the correlation of clinical and functional staging was highly significant (p<0.01). Conclusions: The widespread habit of chewing gutkha is a major risk factor for OSMF, especially in the younger age group. In this study, it was found that with increase in the duration and frequency of the habit the severity of the disease increased.

#OSMF #habits #frequency #duration #clinical staging #functional staging #histopathological grading

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