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논문 기본 정보

자료유형
학술저널
저자정보
Abusail, Mustafa Saadalnour (Department of Histopathology and Cytology, Faculty of Medical laboratory Sciences, Elneelain University) Dirweesh, Ahmed Mohmed Ahmed (Medicine, University of Hail, Kingdom of Saudi Arabia) Salih, Rashid Awad Abdalla (Medicine, University of Hail, Kingdom of Saudi Arabia) Gadelkarim, Ahmed Hussain (Medicine, University of Hail, Kingdom of Saudi Arabia)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제14권 제11호
발행연도
2013.1
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6,415 - 6,418 (4page)

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Background: The aim of this study was to assess EGFR and p53 expression in head and neck tumors among Sudanese patients using immunohistochemistry. Materials and Methods: A retrospective descriptive study was performed on 150 samples from patients diagnosed with HNCs as well as 50 from individuals with benign head and neck tumors. EGFR and p53 expression was assessed using immunohistochemistry (IHC). Results: EGFR was expressed in 126/150 (84%) of HNCS and 6/50 (12%) benign head and neck tumors where as p53 was expressed in 29/150 (19.3%) of HNCs and 2/50 (4%) of benign head and neck tumors, with significance at p values of 0.001 and 0.009 respectively. Conclusions: There is a significant association between EGFR, P53 expression and head and neck cancers among Sudanese patients.

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