Improved Detection of Helicobacter pylori Infection and Premalignant Gastric Mucosa Using Conventional White Light Source Gastroscopy

Matrakool, Likit; Tongtawee, Taweesak; Bartpho, Theeraya; Dechsukhum, Chavaboon; Loyd, Ryan A; Kaewpitoon, Soraya J; Kaewpitoon, Natthawut

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자료유형: 학술저널

저자정보: Matrakool, Likit (School of Surgery, Institute of Medicine, Suranaree University of Technology) Tongtawee, Taweesak (School of Surgery, Institute of Medicine, Suranaree University of Technology) Bartpho, Theeraya (School of Surgery, Institute of Medicine, Suranaree University of Technology) Dechsukhum, Chavaboon (School of Pathology, Institute of Medicine, Suranaree University of Technology) Loyd, Ryan A (School of Family Medicine and Community Medicine, Institute of Medicine, Suranaree University of Technology) Kaewpitoon, Soraya J (School of Family Medicine and Community Medicine, Institute of Medicine, Suranaree University of Technology) Kaewpitoon, Natthawut (Faculty of Public health, Vongchavalitkul University)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제17권 제4호

발행연도: 2016.1

수록면: 2,099 - 2,103 (5page)

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Background: The gold standard diagnosis of H. pylori related gastritis is evidence of bacteria on histopathological examination of gastric mucosa. Our aim was to study the correlation between gastric mucosal morphology and histopathological severity of H. pylori related gastritis. Materials and Methods: Division was made on morphological features into:Type 1, showing regular arrangement of red dots; Type 2, showing cleft-like appearance; Type 3, with a mosaic appearance; and Type 4, having a mosaic appearance with focal or diffuse hyperemia. Results: Types 1 and 2 gastric mucosal morphologies were statistically significant in predicting an H. pylori negative status (137/145, p<0.01), while Types 3 and 4 were significant a positive status (139/155, p<0.01). The sensitivity, specificity, positive and negative predictive values of Type 3 and 4 morphologies for predicting H. pylori positive were 94.6%, 89.5%, 89.7% and 94.5%, respectively, with a good correlation with inflammation grading (p<0.01). Conclusions: Our study suggests that gastric mucosal morphology can be reliably identified using conventional white light source gastroscopy with good correlation between findings and inflammation grading.

#Gastric mucosa #premalignant gastric lesion #conventional white light source gastroscopy #H pylori

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