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학술저널
저자정보
Wang, Rui-Tao (Department of hepatobiliary surgery, the First Affiliated Hospital, School of Medicine, Xi'an Jiaotong University) Xu, Xin-Sen (Department of hepatobiliary surgery, the First Affiliated Hospital, School of Medicine, Xi'an Jiaotong University) Liu, Jun (Department of hepatobiliary surgery, the First Affiliated Hospital, School of Medicine, Xi'an Jiaotong University) Liu, Chang (Department of hepatobiliary surgery, the First Affiliated Hospital, School of Medicine, Xi'an Jiaotong University)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제13권 제6호
발행연도
2012.1
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2,511 - 2,514 (4page)

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Objective: To evaluate the prognostic factors of gallbladder carcinoma. Methods: Presentation, operative data, complications, and survival outcome were examined for 132 gallbladder carcinoma patients who underwent gallbladder surgery in our unit during 2002-2007, and follow-up results were obtained from every patient for univariate and multivariate survival analysis. Results: The univariate analysis showed that gallbladder lesion history, tumor cell differentiation, Nevin staging, preoperative lymph node metastasis and the surgical approach significantly correlated with the prognosis of the patients (p<0.05). The results of the multivariate analysis (Cox regression) showed that gallbladder lesion history, Nevin staging and the surgical approach were independent predicators with relative risks of 6.9, 4.4, 2.8, respectively (p=0.002, 0.003, 0.008). Conclusion: Gallbladder lesion history, Nevin staging and the surgical approach are independent prognostic factors for gallbladder carcinoma, a rapidly fatal disease. Therefore, early diagnosis, anti-infective therapy and radical surgery are greatly needed to improve the prognosis of gallbladder carcinoma.

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